@article{uoadl:2997407, volume = "348", journal = "Journal of Neuroimmunology", issn = "0165-5728", keywords = "cholinergic receptor antibody; enzyme antibody; immunoglobulin; muscle specific tyrosine kinase antibody; prednisolone; pyridostigmine; rituximab; unclassified drug; autoantibody; autoantigen; cholinergic receptor; MUSK protein, human; protein tyrosine kinase, adult; antibody detection; antibody titer; Article; bone density; case report; clinical article; clinical feature; diplopia; disease severity; drug dose reduction; drug efficacy; dysarthria; dysphagia; fatigue; female; human; mastication; myasthenia gravis; Myasthenia Gravis Composite scale; neurologic examination; priority journal; radioimmunoprecipitation; rating scale; serology; immunology; myasthenia gravis, Adult; Autoantibodies; Autoantigens; Female; Humans; Myasthenia Gravis; Receptor Protein-Tyrosine Kinases; Receptors, Cholinergic", BIBTEX_ENTRY = "article", year = "2020", author = "Zouvelou, V. and Psimenou, E.", abstract = "This is a report of an early onset AChR-and MuSK-positive myasthenia gravis. The double seropositivity was detected at the onset of the disease and persisted during 3.5 years follow-up despite the chronic immunotherapy and thymectomy. It is the second reported case of this rare immunological coexistence with sufficient follow-up and available clinical details. At the detection of double positive AChR and MuSK Abs, the treating physician often feels unsecure about the optimal treatment strategy and the long-term prognosis. The detailed clinical record and the long observation of these rare cases, are mandatory for best management in clinical practice. © 2020", title = "AChR-and MuSK-positive myasthenia gravis: Double trouble", doi = "10.1016/J.JNEUROIM.2020.577364" }