@article{uoadl:3126329, volume = "35", number = "2", pages = "173-178", journal = "Clinics in Dermatology", issn = "0738-081X", keywords = "adapalene; antibiotic agent; azelaic acid; benzoyl peroxide; clindamycin; dapsone; erythromycin; isotretinoin; retinoic acid; retinoid; tazarotene; tetracycline; antiinfective agent; azelaic acid; benzoyl peroxide; dapsone; dermatological agent; dicarboxylic acid; retinoid, acne; antibacterial activity; antibiotic resistance; antiinflammatory activity; Article; burning sensation; dermatitis; desquamation; drug efficacy; drug safety; dysesthesia; human; monotherapy; nonhuman; postinflammatory hyperpigmentation; prescription; Propionibacterium acnes; pruritus; acne vulgaris; topical drug administration, Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Anti-Infective Agents; Benzoyl Peroxide; Dapsone; Dermatologic Agents; Dicarboxylic Acids; Humans; Retinoids", BIBTEX_ENTRY = "article", year = "2017", author = "Kosmadaki, M. and Katsambas, A.", abstract = "Topical drugs have been used successfully to treat acne for decades. This review discusses the use, efficacy, and safety of options available via prescription. Topical antibiotics, dapsone, benzyl peroxide, azelaic acid, and topical retinoids are included. Topical antibiotics should not be used as monotherapy but rather be combined with other agents to avoid resistant Propionibacterium acnes strains. Benzoyl peroxide is effective in preventing bacteria resistance. Topical retinoids address primarily the comedonal but also the inflammatory lesions of acne. Azelaic acid is useful in treating acne lesions and for lightening postinflammatory hyperpigmentation that may accompany inflammatory acne lesions. Combinations of agents that address different aspects of acne pathogenesis may offer higher benefit to acne patients. © 2016 Elsevier Inc.", title = "Topical treatments for acne", doi = "10.1016/J.CLINDERMATOL.2016.10.010" }