@article{uoadl:3348391,
    volume = "24",
    number = "2",
    pages = "256-265",
    journal = "International Journal of Stroke",
    issn = "1747-4930, 1747-4949",
    keywords = "Article;  cerebral sinus thrombosis;  cerebrovascular accident;  computer assisted tomography;  coronavirus disease 2019;  health impact assessment;  hospital mortality;  hospitalization;  human;  ICD-10;  ischemic stroke;  laboratory test;  major clinical study;  mechanical thrombectomy;  mortality;  neuroimaging;  nuclear magnetic resonance imaging;  pandemic;  subarachnoid hemorrhage;  vaccine-induced immune thrombotic thrombocytopenia",
    BIBTEX_ENTRY = "article",
    year = "2022",
    author = "Nguyen, T.N. and Qureshi, M.M. and Klein, P. and Yamagami, H. and Abdalkader, M. and Mikulik, R. and Sathya, A. and Mansour, O.Y. and Czlonkowska, A. and Lo, H. and Field, T.S. and Charidimou, A. and Banerjee, S. and Yaghi, S. and Siegler, J.E. and Sedova, P. and Kwan, J. and de Sousa, D.A. and Demeestere, J. and Inoa, V. and Omran, S.S. and Zhang, L. and Michel, P. and Strambo, D. and Marto, J.P. and Nogueira, R.G. and Lereis, V.P. and Ma, A. and Enzinger, C. and Gattringer, T. and Rahman, A. and Bonnet, T. and De Raedt, S. and Lemmens, R. and Ligot, N. and Vandervorst, F. and Conforto, A.B. and Hidalgo, R.C.T. and Cuervo, D.L.M. and Neves, L.O. and da Silva, I.L. and Martins, R.T. and Rebello, L.C. and Santiago, I.B. and Alexiev, F. and Sakelarova, T. and Kalpachki, R. and Cora, E.A. and Kelly, M.E. and Pikula, A. and Chen, H.-S. and Chen, Y. and Yang, S. and Bedekovic, M.R. and Čabal, M. and Tenora, D. and Dušek, P. and Fibrich, P. and Hrabanovska, E. and Hlaváčová, H. and Jurák, L. and Kadlckova, J. and Karpowicz, I. and Klečka, L. and Kovář, M. and Neumann, J. and Paloušková, H. and Reiser, M. and Rohan, V. and Skoda, O. and Škorňa, M. and Šimůnek, L. and Šrámek, M. and Drenck, N. and Sobh, K. and Strbian, D. and Lesaine, E. and Reiner, P. and Rouanet, F. and Sabben, C. and Boskamp, S. and Mbroh, J. and Nagel, S. and Poli, S. and Rosenkranz, M. and Thomalla, G. and Karapanayiotides, T. and Kargiotis, O. and Koutroulou, I. and Palaiodimou, L. and Tsivgoulis, G. and Guerra, J.D.B. and Huded, V. and Nagendra, S. and Prajapati, C. and Sylaja, P.N. and Sani, A.F. and Ghoreishi, A. and Hashemilar, M. and Sadeghi-Hokmabadi, E. and Rahal, F. and Sabetay, S.I. and Acampa, M. and Adami, A. and Longoni, M. and Ornello, R. and Renieri, L. and Romoli, M. and Sacco, S. and Salmaggi, A. and Sangalli, D. and Zini, A. and Fujita, K. and Fukuda, H. and Matsumaru, Y. and Miyake, K. and Ohara, N. and Sakaguchi, M. and Sakai, K. and Shindo, S. and Sonoda, K. and Sugiura, Y. and Takenobu, Y. and Toyoda, K. and Uwatoko, T. and Yamamoto, R. and Yazawa, Y. and Yoshimoto, T. and Baek, J.-H. and Lee, J.S. and Lee, S.B. and Seo, K.-D. and Sohn, S.-I. and Arsovska, A.A. and Chieh, C.Y. and Zaidi, W.A.W. and Yahya, W.N.N.W. and Gongora-Rivera, F. and Martinez-Marino, M. and Infante-Valenzuela, A. and Dippel, D. and van Dam-Nolen, D.H.K. and Punter, M. and Wu, T.Y. and Sunmonu, T.A. and Adebayo, T.T. and Wahab, K.W. and Bello, A.H. and Sundseth, A. and Kristoffersen, E.S. and Al Hashmi, A.M. and Ahmad, S. and Rashid, U. and Rodriguez-Kadota, L. and Vences, M.Á. and Yalung, P.M. and Brola, W. and Dębiec, A. and Dorobek, M. and Karlinski, M.A. and Labuz-Roszak, B.M. and Lasek-Bal, A. and Sienkiewicz-Jarosz, H. and Staszewski, J. and Sobolewski, P. and Wiącek, M. and Zielinska-Turek, J. and Araújo, A.P. and Ferreira, P. and Fonseca, L. and Nunes, A.P. and Silva, M.L. and Castro, P. and Rocha, M. and Rodrigues, M. and Pinho E Melo, T. and Ciopleias, B. and Dimitriade, A. and Falup-Pecurariu, C. and Venketasubramanian, N. and Krastev, G. and Haring, J. and Ayo-Martin, O. and Blasco, J. and Cruz-Culebras, A. and Hernandez-Fernandez, F. and Moniche, F. and Guillan, M. and Sánchez, M.J.G. and Montaner, J. and Perez-Sanchez, S. and Rodríguez-Vázquez, A. and Bolognese, M. and Bernava, G. and Carrera, E. and Churojana, A. and Aykac, O. and Bajrami, A. and Ozdemir, A.O. and Senadim, S. and Hussain, S.I. and John, S. and Krishnan, K. and Lenthall, R. and Asif, K.S. and Biller, J. and Below, K. and Chebl, A. and Chen, M. and Colasurdo, M. and Czap, A. and Dharmadhikari, S. and de Havenon, A.H. and Eskey, C.J. and Farooqui, M. and Feske, S.K. and Goyal, N. and Grimmett, K.B. and Guzik, A.K. and Haussen, D.C. and Hovingh, M. and Jillela, D. and Kan, P.T. and Khatri, R. and Khoury, N.N. and Kiley, N.L. and Kolikonda, M.K. and Lara, S. and Li, G. and Linfante, I. and Loochtan, A.I. and Lopez, C.D. and Lycan, S. and Male, S.S. and Maali, L. and Masoud, H.E. and Min, J. and Mohamed, G.A. and Mohammaden, M. and Nahab, F. and Nalleballe, K. and Ortega-Gutierrez, S. and Radaideh, Y. and Ramakrishnan, P. and Rayo-Taranto, B. and Rojas-Soto, D.M. and Ruland, S. and Sheth, S.A. and Simpkins, A.N. and Starosciak, A.K. and Tarlov, N.E. and Taylor, R.A. and Voetsch, B. and Zhang, L. and Duong, H.Q. and Vu Le, H. and Pham, T.N. and Tran, A.D. and Ton, M.D. and Dao, V.-P. and Zaidat, O.O. and Machi, P. and Dirren, E. and Fernández, C.R. and López, J.E. and Ferro, J.C.F. and Mohammadzadeh, N. and Suryadevara, N.C. and Jancar, N. and SVIN COVID-19 Global COVID Stroke Registry",
    abstract = "Background and Purpose Recent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year. Methods We conducted a cross-sectional retrospective study of 171 stroke centers from 49 countries. We recorded COVID-19 admission volumes, CVT hospitalization, and CVT in-hospital mortality from January 1, 2019, to May 31, 2021. CVT diagnoses were identified by International Classification of Disease-10 (ICD-10) codes or stroke databases. We additionally sought to compare the same metrics in the first 5 months of 2021 compared to the corresponding months in 2019 and 2020 (ClinicalTrials.gov Identifier: NCT04934020). Results There were 2,313 CVT admissions across the 1-year pre-pandemic (2019) and pandemic year (2020); no differences in CVT volume or CVT mortality were observed. During the first 5 months of 2021, there was an increase in CVT volumes compared to 2019 (27.5%; 95% confidence interval [CI], 24.2 to 32.0; P<0.0001) and 2020 (41.4%; 95% CI, 37.0 to 46.0; P<0.0001). A COVID-19 diagnosis was present in 7.6% (132/1,738) of CVT hospitalizations. CVT was present in 0.04% (103/292,080) of COVID-19 hospitalizations. During the first pandemic year, CVT mortality was higher in patients who were COVID positive compared to COVID negative patients (8/53 [15.0%] vs. 41/910 [4.5%], P=0.004). There was an increase in CVT mortality during the first 5 months of pandemic years 2020 and 2021 compared to the first 5 months of the pre-pandemic year 2019 (2019 vs. 2020: 2.26% vs. 4.74%, P=0.05; 2019 vs. 2021: 2.26% vs. 4.99%, P=0.03). In the first 5 months of 2021, there were 26 cases of vaccine-induced immune thrombotic thrombocytopenia (VITT), resulting in six deaths. Conclusions During the 1st year of the COVID-19 pandemic, CVT hospitalization volume and CVT in-hospital mortality did not change compared to the prior year. COVID-19 diagnosis was associated with higher CVT in-hospital mortality. During the first 5 months of 2021, there was an increase in CVT hospitalization volume and increase in CVT-related mortality, partially attributable to VITT. © 2022 Korean Stroke Society.",
    title = "Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality",
    doi = "10.5853/JOS.2022.00752"
}