@article{uoadl:3482866,
    volume = "13",
    number = "20",
    journal = "Journal of Clinical Medicine Research",
    issn = "1918-3003, 1918-3011",
    keywords = "adult; Article; body mass; controlled study; electrostimulation; Expanded Disability Status Scale; female; Female Sexual Distress Scale; female sexual dysfunction; Female Sexual Function Index; follow up; human; lubrication; major clinical study; multiple sclerosis; nerve stimulation; neurogenic bladder; overactive bladder; patient satisfaction; pelvis surgery; physical examination; questionnaire; rehabilitation medicine; relapsing remitting multiple sclerosis; sexual function; tibial nerve",
    BIBTEX_ENTRY = "article",
    year = "2024",
    author = "Zachariou, Athanasios and Giannakis, Ioannis and Kaltsas, Aris and Zikopoulos, Athanasios and Skentou, Charikleia and Stavros, Sofoklis and Potiris, Anastasios and Zachariou, Dimitrios and Baltogiannis, Dimitrios and Phuc, Cam Hoang Nguyen and Sopheap, Bou and Tien, Dung Mai Ba and Sofikitis, Nikolaos",
    abstract = "Background/Objectives: Multiple sclerosis (MS) frequently results in both urinary and sexual dysfunction, which significantly impairs quality of life. Conventional treatments for bladder dysfunction often prove insufficient, leading to the exploration of alternative therapies such as percutaneous tibial nerve stimulation (PTNS). This study aimed to assess the impact of PTNS on sexual function and bladder symptoms in female MS patients with neurogenic detrusor overactivity (NDO) and female sexual dysfunction (FSD). Methods: A total of 65 female MS patients with NDO were evaluated and underwent 12 weeks of standardized PTNS treatment. Sexual function was assessed using the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale-Revised (FSDS-R), while bladder symptoms were evaluated using the OAB-v8 questionnaire. Participants were grouped based on the presence of sexual dysfunction and distress and compared to a control group of 20 patients who declined PTNS. Results: Significant improvements were observed in FSFI scores across multiple domains (desire, arousal, lubrication, orgasm, satisfaction, and pain) in the treatment groups (p < 0.05). Additionally, 58.46% of patients showed positive responses to PTNS regarding overactive bladder symptoms (OAB-v8 score), while the control group showed no significant changes. Conclusions: PTNS appears to be an effective therapeutic option for improving sexual function and urinary symptoms in female MS patients with NDO and FSD, offering a promising non-invasive alternative for managing these conditions. © 2024 by the authors.",
    title = "Percutaneous Tibial Nerve Stimulation’s Impact on Sexual Function in Female Patients with Neurogenic Detrusor Overactivity, Sexual Dysfunction, and Multiple Sclerosis",
    doi = "10.3390/JCM13206042"
}