@article{2985733,
    title = "Objective assessment of subjective tinnitus through contralateral suppression of otoacoustic emissions by white noise; suggested cut-off points",
    author = "Riga, M. and Komis, A. and Maragkoudakis, P. and Korres, G. and Danielides, V.",
    journal = "International Journal of Audiology",
    year = "2016",
    volume = "55",
    number = "12",
    pages = "775-781",
    publisher = "Taylor and Francis Ltd.",
    issn = "1499-2027, 1708-8186",
    doi = "10.1080/14992027.2016.1219778",
    keywords = "adult;  auditory stimulation;  cochlea;  evaluation study;  female;  hearing test;  human;  male;  masking;  middle aged;  noise;  pathophysiology;  physiology;  probability;  procedures;  reference value;  sensitivity and specificity;  spontaneous otoacoustic emission;  statistics and numerical data;  tinnitus, Acoustic Stimulation;  Adult;  Cochlea;  Female;  Hearing Tests;  Humans;  Male;  Middle Aged;  Noise;  Otoacoustic Emissions, Spontaneous;  Perceptual Masking;  Probability;  Reference Values;  Sensitivity and Specificity;  Tinnitus",
    abstract = "Objective: Normative otoacoustic emission (OAE) suppression values are currently lacking and the role of cochlear efferent innervation in tinnitus is controversial. The aim of this study was to investigate the association between tinnitus and medial olivocochlear bundle (MOCB) malfunction. Potential suppression amplitude cut-off criteria that could differentiate participants with tinnitus from those without were sought. Design: Mean suppression amplitudes of transient evoked OAEs and distortion product OAEs by contralateral white noise (50 dBSL) were recorded. Six mean suppression amplitudes criteria were validated as possible cut-off points. Study sample: The population consisted of normal hearing (n = 78) or presbycusic adults (n = 19) with tinnitus or without (n = 28 and 13, respectively) chronic tinnitus (in total, n = 138 78 females/60males, aged 49 ± 14 years). Results: Participants with mean suppression values lower than 0.5–1 dBSPL seem to present a high probability to report tinnitus (specificity 88–97%). On the other hand, participants with mean suppression values larger than 2–2.5dBSPL seem to present a high probability of the absence of tinnitus (sensitivity 87–99%). Correlations were stronger among participants with bilateral presence or absence of tinnitus. Conclusions: This study seem to confirm an association between tinnitus and low suppression amplitudes (<1 dBSPL), which might evolve into an objective examination tool, supplementary to conventional audiological testing. © 2016 British Society of Audiology, International Society of Audiology, and Nordic Audiological Society."
}