@article{2985745,
    title = "Physical activity frequency on the 10-year acute coronary syndrome (ACS) prognosis; The interaction with cardiovascular disease history and diabetes mellitus: The greecs observational study",
    author = "Papataxiarchis, E. and Panagiotakos, D.B. and Notara, V. and Kouvari, M. and Kogias, Y. and Stravopodis, P. and Papanagnou, G. and Zombolos, S. and Mantas, Y. and Pitsavos, C.",
    journal = "Journal of aging and physical activity",
    year = "2016",
    volume = "24",
    number = "4",
    pages = "624-632",
    publisher = "Human Kinetics Publishers Inc",
    issn = "1063-8652",
    doi = "10.1123/japa.2015-0267",
    keywords = "acute coronary syndrome;  aged;  clinical trial;  diabetes mellitus;  electrocardiography;  exercise;  female;  Greece;  human;  incidence;  lifestyle;  male;  middle aged;  multicenter study;  pathophysiology;  physiology;  prognosis;  prospective study, Acute Coronary Syndrome;  Aged;  Diabetes Mellitus;  Electrocardiography;  Exercise;  Female;  Greece;  Humans;  Incidence;  Life Style;  Male;  Middle Aged;  Prognosis;  Prospective Studies",
    abstract = "The association between physical activity, diabetes mellitus (DM), and long-term acute coronary syndrome (ACS) prognosis was evaluated. The GREECS study included 2,172 consecutive ACS patients from six Greek hospitals (2003-2004). In 2013-2014, a 10-year follow up was performed with 1,918 patients. Physical activity was categorized in never, rarely (monthly basis), 1-2 and ≥ 3 times/week. Multi-adjusted analysis revealed that 1-2 and ≥ 3 times/week vs. no physical activity had a protective effect on ACS incidence (OR ≥ 0.63 95% CI 0.38, 1.05) and (OR ≥ 0.63 95% CI 0.40, 0.99) respectively, only in patients without prior baseline CVD event. In a subgroup analysis, with DM as strata in these patients, engagement in physical activity (i.e., 1-2 times/week) had a signifcant protective effect among patients with diabetes (OR ≥ 0.51, 95% CI 0.27, 0.96, p ≥.037). These fndings revealed the benefcial role of exercise in secondary ACS prevention, even in DM patients. Public health-oriented policies should incorporate regular physical activity as a key protective factor in disease prognosis. © 2016 Human Kinetics, Inc."
}