@article{2985935, title = "Response of Caenorhabditis elegans to wireless devices radiation exposure", author = "Fasseas, M.K. and Fragopoulou, A.F. and Manta, A.K. and Skouroliakou, A. and Vekrellis, K. and Margaritis, L.H. and Syntichaki, P.", journal = "International Journal of Radiation Biology", year = "2015", volume = "91", number = "3", pages = "286-293", publisher = "Informa Healthcare", issn = "0955-3002, 1362-3095", doi = "10.3109/09553002.2014.995384", keywords = "reactive oxygen metabolite; reactive oxygen metabolite, adult; aging; animal experiment; animal model; apoptosis; Article; assay; Caenorhabditis elegans; chemotaxis; controlled study; developmental stage; electromagnetic radiation; fertility; gene expression; growth; lifespan; marker gene; mobile phone; mutant; nerve degeneration; nonhuman; oxidative stress; practice guideline; priority journal; quantitative analysis; radiation exposure; radiation response; reverse transcription polymerase chain reaction; sham procedure; short term memory; telecommunication; wild type; wireless communication; adverse effects; animal; Caenorhabditis elegans; electromagnetic field; female; gene; growth, development and aging; longevity; male; metabolism; nerve degeneration; physiology; radiation response; radiobiology; transgenic animal; wireless communication, Animalia; Caenorhabditis elegans, Animals; Animals, Genetically Modified; Apoptosis; Caenorhabditis elegans; Cell Phones; Chemotaxis; Electromagnetic Fields; Female; Fertility; Gene Expression; Genes, Helminth; Growth; Longevity; Male; Memory, Short-Term; Nerve Degeneration; Radiobiology; Reactive Oxygen Species; Wireless Technology", abstract = "Purpose: To examine the impact of electromagnetic radiation, produced by GSM (Global System for Mobile communications) mobile phones, Wi-Fi (Wireless-Fidelity) routers and wireless DECT (Digital Enhanced Cordless Telecommunications) phones, on the nematode Caenorhabditis elegans. Materials and methods: We exposed synchronized populations, of different developmental stages, to these wireless devices at E-field levels below ICNIRP's (International Commission on Non-Ionizing Radiation Protection) guidelines for various lengths of time. WT (wild-type) and aging- or stress-sensitive mutant worms were examined for changes in growth, fertility, lifespan, chemotaxis, short-term memory, increased ROS (Reactive Oxygen Species) production and apoptosis by using fluorescent marker genes or qRT-PCR (quantitative Reverse Transcription-Polymerase Chain Reaction). Results: No statistically significant differences were found between the exposed and the sham/control animals in any of the experiments concerning lifespan, fertility, growth, memory, ROS, apoptosis or gene expression. Conclusions: The worm appears to be robust to this form of (pulsed) radiation, at least under the exposure conditions used. © 2015 Informa UK, Ltd." }