@article{2986238, title = "Intrinsic risk factors of noncontact ankle sprains in soccer: A prospective study on 100 professional players", author = "Fousekis, K. and Tsepis, E. and Vagenas, G.", journal = "AMERICAN JOURNAL OF SPORTS MEDICINE", year = "2012", volume = "40", number = "8", pages = "1842-1850", issn = "0363-5465", doi = "10.1177/0363546512449602", keywords = "adult; ankle; ankle injury; article; human; injury; pathophysiology; physiology; risk factor; sport; sport injury; statistical model, Adult; Ankle Injuries; Ankle Joint; Athletic Injuries; Humans; Logistic Models; Risk Factors; Soccer; Sprains and Strains; Young Adult", abstract = "Background: Ankle sprain is an extremely common injury in soccer players. Despite extensive research, the intrinsic cause of this injury under noncontact conditions remains unclear. Purpose: To identify intrinsic risk factors for noncontact ankle sprains in professional soccer players. Study Design: Cohort study; Level of evidence, 2 Methods: One hundred professional soccer players were assessed in the preseason for potential risk factors of noncontact ankle sprains. The assessment included (A) ankle joint asymmetries (right-left) in isokinetic muscle strength, flexibility, proprioception, and stability; (B) somatometric asymmetries; (C) previous injuries; and (D) lateral dominance traits. Noncontact ankle sprains were prospectively recorded and diagnosed for a full competition period (10 months). Results: Seventeen of the players sustained at least 1 noncontact ankle sprain. Logistic regression revealed that players with (A) eccentric isokinetic ankle flexion strength asymmetries (odds ratio [OR] = 8.88; 95% confidence interval [CI], 1.95-40.36, P = .005), (B) increased body mass index (OR = 8.16; 95% CI, 1.42-46.63, P = .018), and (C) increased body weight (OR = 5.72; 95% CI, 1.37-23.95, P = .017 ) each had a significantly higher risk of a noncontact ankle sprain. A trend for younger players (OR = 0.28; 95% CI, 0.061-1.24, P = .092) and for players with ankle laxity asymmetries (OR = 3.38; 95% CI, 0.82-14.00, P = .093) to be at greater risk for ankle sprain was also apparent to the limit of statistical significance (.05