@article{2987133,
    title = "Does route of full feeding affect outcome among ventilated critically ill covid-19 patients: A prospective observational study",
    author = "Karayiannis, D. and Kakavas, S. and Sarri, A. and Giannopoulou, V. and Liakopoulou, C. and Jahaj, E. and Kanavou, A. and Pitsolis, T. and Malachias, S. and Adamos, G. and Mantelou, A. and Almperti, A. and Morogianni, K. and Kampouropoulou, O. and Kotanidou, A. and Mastora, Z.",
    journal = "Nutrient Cycling in Agroecosystems",
    year = "2022",
    volume = "14",
    number = "1",
    publisher = "MDPI",
    issn = "1385-1314",
    doi = "10.3390/nu14010153",
    keywords = "artificial ventilation;  critical illness;  enteric feeding;  epidemiology;  female;  Greece;  human;  intensive care;  length of stay;  male;  middle aged;  mortality;  parenteral nutrition;  procedures;  prospective study;  therapy;  time factor;  treatment outcome, COVID-19;  Critical Care;  Critical Illness;  Enteral Nutrition;  Female;  Greece;  Humans;  Length of Stay;  Male;  Middle Aged;  Parenteral Nutrition;  Prospective Studies;  Respiration, Artificial;  SARS-CoV-2;  Time Factors;  Treatment Outcome",
    abstract = "The outbreak of the new coronavirus strain SARS-CoV-2 (COVID-19) highlighted the need for appropriate feeding practices among critically ill patients admitted to the intensive care unit (ICU). This study aimed to describe feeding practices of intubated COVID-19 patients during their second week of hospitalization in the First Department of Critical Care Medicine, Evaggelismos General Hospital, and evaluate potential associations with all cause 30-day mortality, length of hospital stay, and duration of mechanical ventilation. We enrolled adult intubated COVID-19 patients admitted to the ICU between September 2020 and July 2021 and prospectively monitored until their hospital discharge. Of the 162 patients analyzed (52.8% men, 51.6% overweight/obese, mean age 63.2 ± 1.9 years), 27.2% of patients used parenteral nutrition, while the rest were fed enterally. By 30 days, 34.2% of the patients in the parenteral group had died compared to 32.7% of the patients in the enteral group (relative risk (RR) for the group receiving enteral nutrition = 0.97, 95% confidence interval = 0.88–1.06, p = 0.120). Those in the enteral group demonstrated a lower duration of hospital stay (RR = 0.91, 95% CI = 0.85-0.97, p = 0.036) as well as mechanical ventilation support (RR = 0.94, 95% CI = 0.89–0.99, p = 0.043). Enteral feeding during second week of ICU hospitalization may be associated with a shorter duration of hospitalization and stay in mechanical ventilation support among critically ill intubated patients with COVID-19. © 2021 by the authors. Licensee MDPI, Basel, Switzerland."
}