@article{2987863, title = "Disparate habitual physical activity and dietary intake profiles of elderly men with low and elevated systemic inflammation", author = "Draganidis, D. and Jamurtas, A.Z. and Stampoulis, T. and Laschou, V.C. and Deli, C.K. and Georgakouli, K. and Papanikolaou, K. and Chatzinikolaou, A. and Michalopoulou, M. and Papadopoulos, C. and Tsimeas, P. and Chondrogianni, N. and Koutedakis, Y. and Karagounis, L.G. and Fatouros, I.G.", journal = "Nutrient Cycling in Agroecosystems", year = "2018", volume = "10", number = "5", publisher = "MDPI AG", issn = "1385-1314", doi = "10.3390/nu10050566", keywords = "alpha tocopherol; ascorbic acid; C reactive protein; retinol; antioxidant; C reactive protein; trace element, aged; aging; Article; body composition; body mass; chronic disease; clinical article; controlled study; dietary intake; dual energy X ray absorptiometry; grip strength; human; inflammation; male; muscle mass; nutritional assessment; physical activity; physical performance; accelerometry; diet; exercise; geriatric assessment; Greece; hand strength; health behavior; incidence; inflammation; lifestyle; longitudinal study; metabolism; nutritional status; photon absorptiometry, Absorptiometry, Photon; Accelerometry; Aged; Antioxidants; Body Composition; C-Reactive Protein; Chronic Disease; Diet; Exercise; Geriatric Assessment; Greece; Hand Strength; Health Behavior; Humans; Incidence; Inflammation; Life Style; Longitudinal Studies; Male; Micronutrients; Nutrition Assessment; Nutritional Status", abstract = "The development of chronic, low-grade systemic inflammation in the elderly (inflammaging) has been associated with increased incidence of chronic diseases, geriatric syndromes, and functional impairments. The aim of this study was to examine differences in habitual physical activity (PA), dietary intake patterns, and musculoskeletal performance among community-dwelling elderly men with low and elevated systemic inflammation. Nonsarcopenic older men free of chronic diseases were grouped as ‘low’ (LSI: n = 17; 68.2 ± 2.6 years; hs-CRP: <1 mg/L) or ‘elevated’ (ESI: n = 17; 68.7 ± 3.0 years; hs-CRP: >1 mg/L) systemic inflammation according to their serum levels of high-sensitivity CRP (hs-CRP). All participants were assessed for body composition via Dual Emission X-ray Absorptiometry (DEXA), physical performance using the Short Physical Performance Battery (SPPB) and handgrip strength, daily PA using accelerometry, and daily macro- and micronutrient intake. ESI was characterized by a 2-fold greater hs-CRP value than LSI (p < 0.01). The two groups were comparable in terms of body composition, but LSI displayed higher physical performance (p < 0.05), daily PA (step count/day and time at moderate-to-vigorous PA (MVPA) were greater by 30% and 42%, respectively, p < 0.05), and daily intake of the antioxidant vitamins A (6590.7 vs. 4701.8 IU/day, p < 0.05), C (120.0 vs. 77.3 mg/day, p < 0.05), and E (10.0 vs. 7.5 mg/day, p < 0.05) compared to ESI. Moreover, daily intake of vitamin A was inversely correlated with levels of hs-CRP (r = −0.39, p = 0.035). These results provide evidence that elderly men characterized by low levels of systemic inflammation are more physically active, spend more time in MVPA, and receive higher amounts of antioxidant vitamins compared to those with increased systemic inflammation. © 2018 by the authors. Licensee MDPI, Basel, Switzerland." }