@article{2996813, title = "HLA-B27 frequency in Greek patients with acute anterior uveitis", author = "Zervas, J. and Tsokos, G. and Papadakis, G. and Kabouklis, E. and Papadopoulos, D.", journal = "British Journal of Ophthalmology", year = "1977", volume = "61", number = "11", pages = "699-701", publisher = "BMJ Publishing Group", issn = "0007-1161, 1468-2079", doi = "10.1136/bjo.61.11.699", keywords = "HLA antigen, acute disease; adult; article; comparative study; female; genetics; Greece; human; immunology; iridocyclitis; male; Reiter syndrome; rheumatoid arthritis; sex difference, Acute Disease; Adult; Arthritis, Rheumatoid; Comparative Study; Female; Greece; HLA Antigens; Human; Male; Middle Age; Reiter Disease; Sex Factors; Uveitis, Anterior", abstract = "The histocompatibility antigen HLA-B27 was identified in 12 out of 33 patients with acute non-granulomatous anterior uveitis. This is a frequency of 36·36%, compared with 4·72% in controls. Seven patients had in addition evidence of systemic disease, including ankylosing spondylitis, sacroiliitis, Reiter's disease, Still's disease, and rheumatoid arthritis. Five of these were HLA-B27 positive, which suggests that the uveitis in many of these cases has a similar aetiology to the uveitis in those with rheumatic disease. It appears that the more severe cases of acute anterior uveitis are related more frequently to the presence of HLA-B27." }