@article{2997763,
    title = "How to apply the movement disorder society criteria for diagnosis of progressive supranuclear palsy",
    author = "Grimm, M.-J. and Respondek, G. and Stamelou, M. and Arzberger, T. and Ferguson, L. and Gelpi, E. and Giese, A. and Grossman, M. and Irwin, D.J. and Pantelyat, A. and Rajput, A. and Roeber, S. and van Swieten, J.C. and Troakes, C. and Antonini, A. and Bhatia, K.P. and Colosimo, C. and van Eimeren, T. and Kassubek, J. and Levin, J. and Meissner, W.G. and Nilsson, C. and Oertel, W.H. and Piot, I. and Poewe, W. and Wenning, G.K. and Boxer, A. and Golbe, L.I. and Josephs, K.A. and Litvan, I. and Morris, H.R. and Whitwell, J.L. and Compta, Y. and Corvol, J.-C. and Lang, A.E. and Rowe, J.B. and Höglinger, G.U. and for the Movement Disorder Society-endorsed PSP Study Group",
    journal = "Movement Disorders",
    year = "2019",
    volume = "34",
    number = "8",
    pages = "1228-1232",
    publisher = "John Wiley and Sons Inc",
    issn = "0885-3185, 1531-8257",
    doi = "10.1002/mds.27666",
    keywords = "akinesia;  Article;  autopsy;  cognitive defect;  disease classification;  eye movement disorder;  female;  human;  major clinical study;  male;  medical record review;  motor dysfunction;  movement disorder society criteria;  priority journal;  progressive supranuclear palsy;  retrospective study;  adult;  aged;  body equilibrium;  brain;  classification;  cohort analysis;  medical society;  middle aged;  parkinsonism;  pathology;  pathophysiology;  progressive supranuclear palsy;  sensory dysfunction;  very elderly, Adult;  Aged;  Aged, 80 and over;  Autopsy;  Brain;  Cognitive Dysfunction;  Cohort Studies;  Female;  Humans;  Male;  Middle Aged;  Ocular Motility Disorders;  Parkinsonian Disorders;  Postural Balance;  Retrospective Studies;  Sensation Disorders;  Societies, Medical;  Supranuclear Palsy, Progressive",
    abstract = "Background: The Movement Disorder Society criteria for progressive supranuclear palsy define diagnostic allocations, stratified by certainty levels and clinical predominance types. We aimed to study the frequency of ambiguous multiple allocations and to develop rules to eliminate them. Methods: We retrospectively collected standardized clinical data by chart review in a multicenter cohort of autopsy-confirmed patients with progressive supranuclear palsy, to classify them by diagnostic certainty level and predominance type and to identify multiple allocations. Results: Comprehensive data were available from 195 patients. More than one diagnostic allocation occurred in 157 patients (80.5%). On average, 5.4 allocations were possible per patient. We developed four rules for Multiple Allocations eXtinction (MAX). They reduced the number of patients with multiple allocations to 22 (11.3%), and the allocations per patient to 1.1. Conclusions: The proposed MAX rules help to standardize the application of the Movement Disorder Society criteria for progressive supranuclear palsy. © 2019 International Parkinson and Movement Disorder Society. © 2019 International Parkinson and Movement Disorder Society"
}