@article{2998471, title = "Anatomical and Functional Changes in the Coexistence of Vitreomacular Traction and Epiretinal Membrane: A Spectral-Domain Optical Coherence Tomography Study", author = "Chatziralli, I. and Theodossiadis, G. and Datseris, I. and Parikakis, E. and Theodossiadis, P.", journal = "Ophthalmic Research", year = "2016", volume = "57", number = "1", pages = "54-59", publisher = "S Karger AG", issn = "0030-3747, 1423-0259", doi = "10.1159/000446658", keywords = "aged; anatomical variation; Article; controlled study; cross-sectional study; ellipsoid zone; epiretinal membrane; external limiting membrane; female; human; macular thickness; major clinical study; male; optical coherence tomography device; priority journal; retina macula cystoid edema; retina maculopathy; retrospective study; spectral domain optical coherence tomography; visual acuity; visual system parameters; vitreomacular traction; clinical trial; epiretinal membrane; follow up; macular edema; multicenter study; optical coherence tomography; pathology; pathophysiology; procedures; retina; visual acuity; vitreous body, Aged; Cross-Sectional Studies; Epiretinal Membrane; Female; Follow-Up Studies; Humans; Macular Edema; Male; Retina; Retrospective Studies; Tomography, Optical Coherence; Visual Acuity; Vitreous Body", abstract = "Purpose: The purpose of this study was to evaluate the anatomical and functional findings in patients with vitreomacular traction (VMT) combined with epiretinal membrane (ERM) in the same eye. Methods: In this retrospective, cross-sectional study, we studied 65 patients with VMT and ERM. In 36 of them, ERM/VMT had a 'unified' appearance (group Ι) but in 29, VMT and ERM coexisted without an interrelationship (group ΙΙ). All patients were examined with spectral-domain optical coherence tomography (SD-OCT). We recorded the macular thickness, the presence, type and location of macular edema, the horizontal diameter of VMT, ellipsoid zone/external limiting membrane (EZ/ELM) status, the vitreofoveal angle of VMT nasally and temporally and the best corrected visual acuity (BCVA). Results: Group Ι presented with increased macular thickness, a broader adhesion diameter, extensive EZ/ELM defect and decreased BCVA compared to those where VMT and ERM were not intercorrelated. In group I ('unified' VMT and ERM), cystoid macular edema was found at a greater percentage (41.7%), while in patients where the 2 entities were not intercorrelated, diffuse macular edema was more evident (69%). There was no statistically significant difference between the 2 groups in the vitreofoveal angle temporally and nasally. Conclusions: Macular thickness, type of macular edema, adhesion diameter, the extent of the EZ/ELM defect and BCVA appeared different in cases where VMT and ERM were unified compared to cases where ERM and VMT coexisted but were not intercorrelated. © 2016 S. Karger AG, Basel." }