@article{2999717,
    title = "2021 DORIS definition of remission in SLE: Final recommendations from an international task force",
    author = "van Vollenhoven, R.F. and Bertsias, G. and Doria, A. and Isenberg, D. and Morand, E. and Petri, M.A. and Pons-Estel, B.A. and Rahman, A. and Ugarte-Gil, M.F. and Voskuyl, A. and Arnaud, L. and Bruce, I.N. and Cervera, R. and Costedoat-Chalumeau, N. and Gordon, C. and Houssiau, F.A. and Mosca, M. and Schneider, M. and Ward, M.M. and Alarcon, G. and Aringer, M. and Askenase, A. and Bae, S.-C. and Bootsma, H. and Boumpas, D.T. and Brunner, H. and Clarke, A.E. and Coney, C. and Czirják, L. and Dörner, T. and Faria, R. and Fischer, R. and Fritsch-Stork, R. and Inanc, M. and Jacobsen, S. and Jayne, D. and Kuhn, A. and van Leeuw, B. and Limper, M. and Mariette, X. and Navarra, S. and Nikpour, M. and Olesinska, M.H. and Pons-Estel, G. and Romero-Diaz, J. and Rubio, B. and Schoenfeld, Y. and Bonfá, E. and Smolen, J. and Teng, Y.K.O. and Tincani, A. and Tsang-A-Sjoe, M. and Vasconcelos, C. and Voss, A. and Werth, V.P. and Zakharhova, E. and Aranow, C.",
    journal = "Lupus Science and Medicine",
    year = "2021",
    volume = "8",
    number = "1",
    publisher = "BMJ Publishing Group",
    doi = "10.1136/lupus-2021-000538",
    abstract = "Objective To achieve consensus on a definition of remission in SLE (DORIS). Background Remission is the stated goal for both patient and caregiver, but consensus on a definition of remission has been lacking. Previously, an international task force consisting of patient representatives and medical specialists published a framework for such a definition, without reaching a final recommendation. Methods Several systematic literature reviews were performed and specific research questions examined in suitably chosen data sets. The findings were discussed, reformulated as recommendations and voted on. Results Based on data from the literature and several SLE-specific data sets, a set of recommendations was endorsed. Ultimately, the DORIS Task Force recommended a single definition of remission in SLE, based on clinical systemic lupus erythematosus disease activitiy index (SLEDAI)=0, Evaluator’s Global Assessment <0.5 (0–3), prednisolone 5 mg/day or less, and stable antimalarials, immunosuppressives, and biologics. Conclusion The 2021 DORIS definition of remission in SLE is recommended for use in clinical care, education, and research including clinical trials and observational studies. © 2021 BMJ Publishing Group. All rights reserved."
}