@article{3000199, title = "Toward personalization of asthma treatment according to trigger factors", author = "Niespodziana, K. and Borochova, K. and Pazderova, P. and Schlederer, T. and Astafyeva, N. and Baranovskaya, T. and Barbouche, M.-R. and Beltyukov, E. and Berger, A. and Borzova, E. and Bousquet, J. and Bumbacea, R.S. and Bychkovskaya, S. and Caraballo, L. and Chung, K.F. and Custovic, A. and Docena, G. and Eiwegger, T. and Evsegneeva, I. and Emelyanov, A. and Errhalt, P. and Fassakhov, R. and Fayzullina, R. and Fedenko, E. and Fomina, D. and Gao, Z. and Giavina-Bianchi, P. and Gotua, M. and Greber-Platzer, S. and Hedlin, G. and Ilina, N. and Ispayeva, Z. and Idzko, M. and Johnston, S.L. and Kalayci, Ö. and Karaulov, A. and Karsonova, A. and Khaitov, M. and Kovzel, E. and Kowalski, M.L. and Kudlay, D. and Levin, M. and Makarova, S. and Matricardi, P.M. and Nadeau, K.C. and Namazova-Baranova, L. and Naumova, O. and Nazarenko, O. and O'Byrne, P.M. and Osier, F. and Pampura, A.N. and Panaitescu, C. and Papadopoulos, N.G. and Park, H.-S. and Pawankar, R. and Pohl, W. and Renz, H. and Riabova, K. and Sampath, V. and Sekerel, B.E. and Sibanda, E. and Siroux, V. and Sizyakina, L.P. and Sun, J.-L. and Szepfalusi, Z. and Umanets, T. and Van Bever, H.P.S. and van Hage, M. and Vasileva, M. and von Mutius, E. and Wang, J.-Y. and Wong, G.W.K. and Zaikov, S. and Zidarn, M. and Valenta, R.", journal = "Allergy: European Journal of Allergy and Clinical Immunology", year = "2020", volume = "145", number = "6", pages = "1529-1534", publisher = "Mosby Year Book Inc", doi = "10.1016/j.jaci.2020.02.001", keywords = "allergen; peptide; biological marker, Article; asthma; human; microarray analysis; nonhuman; priority journal; Rhinovirus; serology; virus infection; virus strain; animal; asthma; immunology; metabolism; personalized medicine; procedures, Allergens; Animals; Asthma; Biomarkers; Humans; Precision Medicine; Rhinovirus", abstract = "Asthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma. © 2020 The Authors" }