@article{3000346, title = "Severe asthma: Entering an era of new concepts and emerging therapies: Highlights of the 4th international severe asthma forum, Madrid, 2018", author = "Seys, S.F. and Quirce, S. and Agache, I. and Akdis, C.A. and Alvaro-Lozano, M. and Antolín-Amérigo, D. and Bjermer, L. and Bobolea, I. and Bonini, M. and Bossios, A. and Brinkman, P. and Bush, A. and Calderon, M. and Canonica, W. and Chanez, P. and Couto, M. and Davila, I. and Del Giacco, S. and Del Pozo, V. and Erjefält, J.S. and Gevaert, P. and Hagedoorn, P. and G. Heaney, L. and Heffler, E. and Hellings, P.W. and Jutel, M. and Kalayci, O. and Kurowski, M.M. and Loukides, S. and Nair, P. and Palomares, O. and Polverino, E. and Sanchez-Garcia, S. and Sastre, J. and Schwarze, J. and Spanevello, A. and Ulrik, C.S. and Usmani, O. and Van den Berge, M. and Vasakova, M. and Vijverberg, S. and Diamant, Z.", journal = "Allergy: European Journal of Allergy and Clinical Immunology", year = "2019", volume = "74", number = "11", pages = "2244-2248", publisher = "Wiley-Blackwell Publishing Ltd", doi = "10.1111/all.13843", keywords = "corticosteroid; dupilumab; immunoglobulin E; interleukin 13; interleukin 4; interleukin 5; irritant agent; mepolizumab; microRNA; omalizumab, asthma; bronchiectasis; chronic obstructive lung disease; chronic rhinosinusitis; corticosteroid therapy; disease exacerbation; genomics; human; Letter; metabolic syndrome X; nose polyp; obesity; occupational asthma; patient compliance; patient education; priority journal; pulmonary rehabilitation; respiratory tract inflammation; RNA analysis; severe asthma; severe asthma; transcriptomics; asthma; disease management; disease predisposition; metabolism; severity of illness index, Asthma; Disease Management; Disease Susceptibility; Humans; Severity of Illness Index" }