@article{3000808, title = "Critical view of anaphylaxis epidemiology: Open questions and new perspectives", author = "Tanno, L.K. and Bierrenbach, A.L. and Simons, F.E.R. and Cardona, V. and Thong, B.Y.-H. and Molinari, N. and Calderon, M.A. and Worm, M. and Chang, Y.-S. and Papadopoulos, N.G. and Casale, T. and Demoly, P. and Jakob, R. and Best, L. and Kostanjsek, N. and Chalmers, R.J.G. and Linzer, J. and Edwards, L. and Ayme, S. and Bellet, B. and Franklin, R. and Helbert, M. and Colenbrander, A. and Kashii, S. and Dantas, P.E.C. and Graham, C. and Behrens, A. and Rust, J. and Cumerlato, M. and Suzuki, T. and Kondo, M. and Takizawa, H. and Kohno, N. and Miura, S. and Tajima, N. and Ogawa, T. and and on behalf the Joint Allergy Academies", journal = "Allergy, Asthma and Clinical Immunology", year = "2018", volume = "14", number = "1", pages = "2", publisher = "BioMed Central Ltd.", doi = "10.1186/s13223-018-0234-0", keywords = "epinephrine, anaphylaxis; disease classification; disease severity; emergency ward; hospital admission; human; ICD-11; incidence; morbidity; mortality; prevalence; publication; Review", abstract = "In contrast to the majority of allergic or hypersensitivity conditions, worldwide anaphylaxis epidemiological data remain sparse with low accuracy, which hampers comparable morbidity statistics. Data can differ widely depending on a number of variables. In the current document we reviewed the forms on which anaphylaxis has been defined and classified; and how it can affect epidemiological data. With regards to the methods used to capture morbidity statistics, we observed the impact of the anaphylaxis coding utilizing the World Health Organization's International Classification of Diseases. As an outcome and depending on the anaphylaxis definition, we extracted the cumulative incidence, which may not reflect the real number of new cases. The new ICD-11 anaphylaxis subsection developments and critical view of morbidity statistics data are discussed in order to reach new perspectives on anaphylaxis epidemiology. © 2018 The Author(s)." }