@article{3000990,
    title = "Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines—2016 revision",
    author = "Brożek, J.L. and Bousquet, J. and Agache, I. and Agarwal, A. and Bachert, C. and Bosnic-Anticevich, S. and Brignardello-Petersen, R. and Canonica, G.W. and Casale, T. and Chavannes, N.H. and Correia de Sousa, J. and Cruz, A.A. and Cuello-Garcia, C.A. and Demoly, P. and Dykewicz, M. and Etxeandia-Ikobaltzeta, I. and Florez, I.D. and Fokkens, W. and Fonseca, J. and Hellings, P.W. and Klimek, L. and Kowalski, S. and Kuna, P. and Laisaar, K.-T. and Larenas-Linnemann, D.E. and Lødrup Carlsen, K.C. and Manning, P.J. and Meltzer, E. and Mullol, J. and Muraro, A. and O'Hehir, R. and Ohta, K. and Panzner, P. and Papadopoulos, N. and Park, H.-S. and Passalacqua, G. and Pawankar, R. and Price, D. and Riva, J.J. and Roldán, Y. and Ryan, D. and Sadeghirad, B. and Samolinski, B. and Schmid-Grendelmeier, P. and Sheikh, A. and Togias, A. and Valero, A. and Valiulis, A. and Valovirta, E. and Ventresca, M. and Wallace, D. and Waserman, S. and Wickman, M. and Wiercioch, W. and Yepes-Nuñez, J.J. and Zhang, L. and Zhang, Y. and Zidarn, M. and Zuberbier, T. and Schünemann, H.J.",
    journal = "Allergy: European Journal of Allergy and Clinical Immunology",
    year = "2017",
    volume = "140",
    number = "4",
    pages = "950-958",
    publisher = "Mosby Year Book Inc",
    doi = "10.1016/j.jaci.2017.03.050",
    keywords = "corticosteroid;  histamine H1 receptor antagonist;  leukotriene receptor blocking agent;  antiallergic agent;  histamine H1 receptor antagonist, allergic rhinitis;  ambulatory care;  Article;  asthma;  Delphi study;  disease classification;  evidence based practice;  general practice;  health care cost;  health equity;  human;  job performance;  local adaptation;  practice guideline;  priority journal;  productivity;  quality of life;  school;  systematic review;  animal;  asthma;  child;  clinical decision making;  Rhinitis, Allergic, Animals;  Anti-Allergic Agents;  Asthma;  Child;  Clinical Decision-Making;  Evidence-Based Practice;  Histamine H1 Antagonists;  Humans;  Quality of Life;  Rhinitis, Allergic",
    abstract = "Background: Allergic rhinitis (AR) affects 10% to 40% of the population. It reduces quality of life and school and work performance and is a frequent reason for office visits in general practice. Medical costs are large, but avoidable costs associated with lost work productivity are even larger than those incurred by asthma. New evidence has accumulated since the last revision of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines in 2010, prompting its update. Objective: We sought to provide a targeted update of the ARIA guidelines. Methods: The ARIA guideline panel identified new clinical questions and selected questions requiring an update. We performed systematic reviews of health effects and the evidence about patients’ values and preferences and resource requirements (up to June 2016). We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) evidence-to-decision frameworks to develop recommendations. Results: The 2016 revision of the ARIA guidelines provides both updated and new recommendations about the pharmacologic treatment of AR. Specifically, it addresses the relative merits of using oral H1-antihistamines, intranasal H1-antihistamines, intranasal corticosteroids, and leukotriene receptor antagonists either alone or in combination. The ARIA guideline panel provides specific recommendations for the choice of treatment and the rationale for the choice and discusses specific considerations that clinicians and patients might want to review to choose the management most appropriate for an individual patient. Conclusions: Appropriate treatment of AR might improve patients’ quality of life and school and work productivity. ARIA recommendations support patients, their caregivers, and health care providers in choosing the optimal treatment. © 2017 American Academy of Allergy, Asthma & Immunology"
}