@article{3004526, title = "Antiphospholipid syndrome: A predisposing factor for early onset HELLP syndrome", author = "Tsirigotis, P. and Mantzios, G. and Pappa, V. and Girkas, K. and Salamalekis, G. and Koutras, A. and Giannopoulou, V. and Spirou, K. and Balanika, A. and Papageorgiou, S. and Travlou, A. and Dervenoulas, J.", journal = "Rheumatology International", year = "2007", volume = "28", number = "2", pages = "171-174", issn = "0172-8172, 1437-160X", doi = "10.1007/s00296-007-0386-6", keywords = "acetylsalicylic acid; enoxaparin; immunoglobulin; methylprednisolone, adult; antiphospholipid syndrome; article; blood cell count; case report; computer assisted tomography; disease course; disease predisposition; female; HELLP syndrome; human; laboratory test; medical literature; pregnancy termination; primigravida; priority journal; radiodiagnosis; ultrasound, Abortion, Induced; Adult; Antiphospholipid Syndrome; Female; Genetic Predisposition to Disease; Gestational Age; HELLP Syndrome; Humans; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Pregnancy Trimester, Second", abstract = "Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during the third trimester. Its incidence seems to be increased in patients with antiphospholipid syndrome (APS). In this report, we describe a 33-year-old pregnant woman with previously known primary APS who developed early onset HELLP syndrome during the 15th week of gestation. We also review the literature about this interesting relationship between APS and HELLP. © 2007 Springer-Verlag." }