@article{3009341,
    title = "Serum Bisphenol A concentrations in men with idiopathic infertility",
    author = "Mantzouki, C. and Bliatka, D. and Iliadou, P.K. and Margeli, A. and Papassotiriou, I. and Mastorakos, G. and Kousta, E. and Goulis, D.G.",
    journal = "Food and Chemical Toxicology",
    year = "2019",
    volume = "125",
    pages = "562-565",
    publisher = "Elsevier Ireland Ltd",
    issn = "0278-6915, 1873-6351",
    doi = "10.1016/j.fct.2019.02.016",
    keywords = "4,4' isopropylidenediphenol;  Muellerian inhibiting factor;  4,4' isopropylidenediphenol;  benzhydryl derivative;  endocrine disruptor;  Muellerian inhibiting factor;  phenol derivative, adult;  Article;  azoospermia;  blood analysis;  case control study;  causal attribution;  clinical assessment;  controlled study;  cross-sectional study;  cryptorchism;  disease association;  exposure;  hormone blood level;  hormone determination;  human;  idiopathic disease;  major clinical study;  male;  men's health;  sperm quality;  spermatozoon abnormality;  spermatozoon motility;  varicocele;  blood;  male infertility;  semen analysis, Adult;  Anti-Mullerian Hormone;  Benzhydryl Compounds;  Endocrine Disruptors;  Humans;  Infertility, Male;  Male;  Phenols;  Semen Analysis",
    abstract = "Background: Bisphenol A (BPA) has been associated with male reproductive dysfunction. However, few studies have assessed BPA according to the cause of male infertility. Aim: To investigate serum BPA concentrations in infertile men according to infertility cause. Patients and methods: Men with infertility (n = 55) [non-obstructive azoospermia (n = 23), cryptorchidism (n = 12), varicocele (n = 20)] compared with fertile men (n = 25). Serum BPA concentrations were measured along with clinical and hormonal assessment. Results: BPA was detected in all men, with no difference between infertile and control groups [median (IQR) 0.19 (0.45) vs. 0.18 (0.28) ng/ml, p = 0.689] or among the infertility cause [azoospermia 0.30 (0.69), cryptorchidism 0.12 (0.39), varicocele 0.17 (0.23) ng/ml, p = 0.316]. High concentrations of BPA (>3 ng/ml) were observed only in infertile men. Α negative correlation was observed between ΒΡΑ concentrations and AMH (r = −0.320, p < 0.01). Conclusions: Although male infertility cannot be attributed to exposure to BPA, high concentrations of BPA could contribute to infertility. © 2019 Elsevier Ltd"
}