@article{3009751,
    title = "The role of coffee consumption on the 10-year (2004-2014) Acute Coronary Syndrome (ACS) incidence among cardiac patients: The GREECS observational study",
    author = "Notara, V. and Panagiotakos, D.B. and Kouvari, M. and Tzanoglou, D. and Kouli, G. and Mantas, Y. and Kogias, Y. and Stravopodis, P. and Papanagnou, G. and Zombolos, S. and Babatsikou, F. and Koutis, C. and Pitsavos, C.",
    journal = "International Journal of Food Sciences and Nutrition",
    year = "2015",
    volume = "66",
    number = "6",
    pages = "722-728",
    publisher = "Taylor and Francis Ltd.",
    issn = "0963-7486, 1465-3478",
    doi = "10.3109/09637486.2015.1077795",
    keywords = "coffee, acute coronary syndrome;  adverse effects;  aged;  coffee;  complication;  female;  human;  hypertension;  incidence;  male;  middle aged;  odds ratio;  risk factor;  statistical model;  very elderly, Acute Coronary Syndrome;  Aged;  Aged, 80 and over;  Coffee;  Female;  Humans;  Hypertension;  Incidence;  Logistic Models;  Male;  Middle Aged;  Odds Ratio;  Risk Factors",
    abstract = "The association between long-term coffee consumption and 10-year cardiovascular disease incidence among Acute Coronary Syndrome (ACS) patients was evaluated. From 2003 to 2004, 2172 ACS consecutive patients from six major Greek hospitals were enrolled. During 2013-2014, the 10-year follow-up was performed (88% participation rate) and recurrent fatal or nonfatal ACS was recorded. Baseline coffee consumption (cups/day) was assessed using a semiquantitative Food Frequency Questionnaire. Multi adjusted analysis revealed that 1-2 cups of coffee/day versus no consumption had an adverse effect on the ACS incidence [odds ratio (OR) = 1.35, 95% confidence interval (CI) 1.01, 1.79]. In subgroup analysis, with hypertension as strata, only the normotensive reached significance. Odds ratios for 1-2 and ≥3 cups relative to no consumption were [OR = 1.66, 95% CI 1.07, 2.60] and [OR = 1.86, 95% CI 1.06, 3.27], respectively, after controlling for potential confounders. Thus, avoidance of coffee may be of high importance to ameliorate disease prognosis among cardiac patients. © 2015 Taylor & Francis."
}