@article{3009953, title = "Secondary metabolites from the aerial parts of Centaurea pannonica (Heuff.) Simonk. from Serbia and their chemotaxonomic importance", author = "Ifantis, T.M. and Solujić, S. and Pavlović-Muratspahić, D. and Skaltsa, H.", journal = "Phytochemistry", year = "2013", volume = "94", pages = "159-170", publisher = "Elsevier Ireland Ltd", issn = "0031-9422", doi = "10.1016/j.phytochem.2013.05.014", keywords = "Centaurea; Centaurea jacea, flavonoid; germacranolide; lactone; lignan; plant extract; salonitenolide; sesquiterpene, article; C. pannonica (Heuff.) Simonk.; Centaurea; Centaurea jacea group; Centaurea L.; chemical structure; chemistry; chemotaxonomy; classification; conformation; Guaianolides; isolation and purification; metabolism; nuclear magnetic resonance; nuclear magnetic resonance spectroscopy; plant; Serbia; species difference, C. pannonica (Heuff.) Simonk.; Centaurea jacea group; Centaurea L.; Chemotaxonomy; Flavonoids; Guaianolides; Lignans; NMR, Centaurea; Flavonoids; Lactones; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Plant Components, Aerial; Plant Extracts; Serbia; Sesquiterpenes; Sesquiterpenes, Germacrane; Species Specificity", abstract = "The non polar extract of Centaurea pannonica (Heuff.) Simonk., growing wild in Serbia, was studied and twenty-five compounds including 14 sesquiterpene lactones, 7 flavonoids, 3 lignans and 1 phenylpropanoid glycoside were isolated. All compounds were isolated for the first time from this species. Among them, one germacranolide 2α-hydroxy, 8-dehydroxy 15-O-methacrylate salonitenolide (1) and two guai-anolides 2α,8α-dihydroxy- dehydrocostus lactone (2) and pannonin (3) are new natural compounds. The structures of the compounds were established on the basis of spectroscopic analyses (UV, IR, HREIMS and 1D & 2D NMR). The chemical profile of C pannonica, which belongs to the "Centaurea jacea" group, was compared to previously studied taxa of the same group and used to assess the phylogenetic relationships in the group. © 2013 Elsevier Ltd. All rights reserved." }