@article{3022984,
    title = "Preliminary evaluation of somaclonal variation for the in vitro production of new toxic proteins from Viscum album L.",
    author = "Kintzios, S. and Barberaki, M. and Tourgielis, P. and Aivalakis, G. and Volioti, A.",
    journal = "Journal of Herbs, Spices and Medicinal Plants",
    year = "2002",
    volume = "9",
    number = "2-3",
    pages = "217-221",
    publisher = "Taylor and Francis Inc.",
    doi = "10.1300/J044v09n02_31",
    keywords = "vegetable protein, protein, conference paper;  in vitro study;  nonhuman;  plant stem;  plant tissue;  polyacrylamide gel electrophoresis;  protein content;  protein synthesis;  quantitative analysis;  somaclonal variation;  tissue culture;  Viscum album, Viscum;  Viscum album;  Viscum album",
    abstract = "In an attempt at preliminary evaluation of the effect of somaclonal variation on the production of white berry mistletoe (Viscum album L.) proteins, one hundred individual callus tissues were assayed for their protein content by means of SDS-PAGE. Somaclonal variation in the qualitative aspect was relatively low (8%). However, variation in quantitative terms was high and in 10% of the calli a protein concentration six times higher than in stems was observed. These results indicate for the first time the possibility of applying tissue culture for the production of mistletoe protein extracts with increased antitumor/immunomodulatory properties. © 2002 by The Haworth Press, Inc. All rights reserved."
}