@article{3025660,
    title = "V1-methyl-8-phenyl-1,3-diazaspiro[4.5]decane-2,4-dione",
    author = "Pardali, V. and Katsamakas, S. and Giannakopoulou, E. and Zoidis, G.",
    journal = "MolBank",
    year = "2021",
    volume = "2021",
    number = "2",
    publisher = "MDPI AG",
    doi = "10.3390/M1228",
    abstract = "A simple, fast and cost-effective three-step synthesis of 1-methyl-8-phenyl-1,3-diazaspiro[4.5] decane-2,4-dione has been developed. The reactions described herein proceed readily, with high yields and no further purification. Therefore, the proposed method, with an overall yield of 60%, offers a facile pathway to the synthesis of N-1 monosubstituted spiro carbocyclic imidazolidine-2,4-diones (hydantoins), which constitute a privileged class of heterocyclic scaffolds with pharmacological interest. © 2021 by the authors. Licensee MDPI, Basel, Switzerland."
}