@article{3025955,
    title = "Vagiallene, a Rearranged C 15 Acetogenin from Laurencia obtusa",
    author = "Perdikaris, S. and Mangoni, A. and Grauso, L. and Papazafiri, P. and Roussis, V. and Ioannou, E.",
    journal = "Organic Letters",
    year = "2019",
    volume = "21",
    number = "9",
    pages = "3183-3186",
    publisher = "American Chemical Society",
    issn = "1523-7060, 1523-7052",
    doi = "10.1021/acs.orglett.9b00897",
    keywords = "acetogenin;  antineoplastic agent;  plant extract, cell survival;  chemical structure;  chemistry;  conformation;  drug effect;  human;  isolation and purification;  isomerism;  Laurencia;  molecular dynamics;  quantum theory;  thermodynamics;  tumor cell line, Acetogenins;  Antineoplastic Agents;  Cell Line, Tumor;  Cell Survival;  Humans;  Isomerism;  Laurencia;  Molecular Conformation;  Molecular Dynamics Simulation;  Molecular Structure;  Plant Extracts;  Quantum Theory;  Thermodynamics",
    abstract = "Vagiallene (1), a rearranged C 15 acetogenin with a molecular formula and a carbon skeleton unprecedented in natural products, was isolated as a trace constituent from the organic extract of the red alga Laurencia obtusa from Lefkada island. The planar structure and the relative configuration of 1 were established on the basis of extensive analysis of its spectroscopic data, while its absolute configuration was determined by comparison of its experimental and quantum-mechanically predicted electronic circular dichroism spectra. © 2019 American Chemical Society."
}