@article{3027174, title = "Design and synthesis of some new pyranoxanthenones with cytotoxic activity", author = "Ghirtis, K. and Pouli, N. and Marakos, P. and Skaltsounis, A.-L. and Leonce, S. and Atassi, G. and Caignard, D.H.", journal = "Journal of Heterocyclic Chemistry", year = "2001", volume = "38", number = "1", pages = "147-152", issn = "0022-152X, 1943-5193", doi = "10.1002/jhet.5570380121", keywords = "acronine; bromine derivative; cytotoxic agent; pyranoxanthone derivative; unclassified drug, animal cell; article; cell proliferation; drug cytotoxicity; drug design; drug synthesis; mouse; nonhuman; reaction analysis; structure analysis", abstract = "As part of a research program directed towards the design and synthesis of pyranoxanthones structurally related to acronycine, we present here the synthesis and cytotoxic activity of the pyranoxanthones 3 and 4 (X= H, Br; R= H, OMe; R'= H, Ac). Some of these compounds inhibit L1210 cell proliferation." }