@article{3029480,
    title = "The COVID-19 Pandemic and the Need for an Integrated and Equitable
Approach: An International Expert Consensus Paper",
    author = "Gerotziafas, Grigoris T. and Catalano, Mariella and Theodorou, Yiannis and and Van Dreden, Patrick and Marechal, Vincent and Spyropoulos, Alex C. and and Carter, Charles and Jabeen, Nusrat and Harenberg, Job and Elalamy, and Ismail and Falanga, Anna and Fareed, Jawed and Agathaggelou, Petros and and Antic, Darko and Antignani, Pier Luigi and Bosch, Manuel Monreal and and Brenner, Benjamin and Chekhonin, Vladimir and Colgan, Mary-Paula and and Dimopoulos, Meletios-Athanasios and Douketis, Jim and Elnazar, Essam Abo and and Farkas, Katalin and Fazeli, Bahare and Fowkes, Gerry and Gu, and Yongquan and Gligorov, Joseph and Ligocki, Mark A. and Indran, Tishya and and Kannan, Meganathan and Kantarcioglu, Bulent and Kasse, Abdoul Aziz and and Konstantinidis, Kostantinos and Leivano, Fabio and Lewis, Joseph and and Makatsariya, Alexander and Mbaye, P. Massamba and Mahe, Isabelle and and Panovska-Stavridis, Irina and Olinic, Dan-Mircea and Papageorgiou, and Chryssa and Pecsvarady, Zsolt and Pillon, Sergio and Ramacciotti, and Eduardo and Abdel-Razeq, Hikmat and Sabbah, Michele and Sassi, Mouna and and Schernthaner, Gerit and Siddiqui, Fakiha and Shiomura, Jin and and Slama-Schwok, Anny and Wautrecht, Jean Claude and Tafur, Alfonso and and Taher, Ali and Klein-Wegel, Peter and Zhai, Zenguo and Zoubida, Tazi and Mezalek",
    journal = "Thrombosis and Haemostasis",
    year = "2021",
    volume = "121",
    number = "08",
    pages = "992-1007",
    publisher = "Georg Thieme Verlag KG",
    issn = "0340-6245",
    doi = "10.1055/a-1535-8807",
    keywords = "COVID-19; SARS-CoV-2; pandemic; thrombosis; health care systems",
    abstract = "Background One year after the declaration of the coronavirus disease
2019 (COVID-19) pandemic by the World Health Organization (WHO) and
despite the implementation of mandatory physical barriers and social
distancing, humanity remains challenged by a long-lasting and
devastating public health crisis.
Management Non-pharmacological interventions (NPIs) are efficient
mitigation strategies. The success of these NPIs is dependent on the
approval and commitment of the population. The launch of a mass
vaccination program in many countries in late December 2020 with mRNA
vaccines, adenovirus-based vaccines, and inactivated virus vaccines has
generated hope for the end of the pandemic.
Current Issues The continuous appearance of new pathogenic viral strains
and the ability of vaccines to prevent infection and transmission raise
important concerns as we try to achieve community immunity against
severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) and
its variants. The need of a second and even third generation of vaccines
has already been acknowledged by the WHO and governments.
Perspectives There is a critical and urgent need for a balanced and
integrated strategy for the management of the COVID-19 outbreaks
organized on three axes: (1) P revention of the SARS-CoV-2 infection,
(2) Detection and early diagnosis of patients at risk of disease
worsening, and (3) Anticipation of medical care (PDA).
Conclusion The “PDA strategy” integrated into state policy for the
support and expansion of health systems and introduction of digital
organizations (i.e., telemedicine, e-Health, artificial intelligence,
and machine-learning technology) is of major importance for the
preservation of citizens’ health and life world-wide."
}