@article{3029698,
    title = "Assessment of Antioxidant and Antimutagenic Properties of Red and White
Wine Extracts In Vitro",
    author = "Tekos, Fotios and Makri, Sotiria and Skaperda, Zoi-Vasiliki and Patouna, and Anastasia and Terizi, Kallirroi and Kyriazis, Ioannis D. and Kotseridis, and Yorgos and Mikropoulou, Eleni Vaskani and Papaefstathiou, Georgios and and Halabalaki, Maria and Demetrios, Kouretas",
    journal = "Cell Metabolism",
    year = "2021",
    volume = "11",
    number = "7",
    publisher = "MDPI",
    doi = "10.3390/metabo11070436",
    keywords = "wine; antioxidants; polyphenols; free radicals; oxidative stress",
    abstract = "Wine is an alcoholic beverage of complex composition obtained through
the fermentation of grape must. The consumption of wine has already been
associated with a multitude of beneficial effects due to its high
polyphenolic content. In this study, four Greek emblematic wines from
two red (i.e., Xinomavro and Agiorgitiko) and two white (i.e., Assyrtiko
and Malagouzia) varieties were analyzed for the estimation of their
antioxidant profiles. To address this question, we assessed their
ability to scavenge both synthetic and endogenous free radicals, such as
DPPH center dot, ABTS(+center dot), OH center dot, O-2(-), their
potential reducing power, and their antimutagenic and antigenotoxic
properties. All varieties exhibited potent antioxidant activity, as
indicated by the results of methods above, with the red wines appearing
more effective than the white ones regarding antioxidant capacity. Our
small-scale study is the first to reveal that these wine varieties may
have the ability to scavenge the most reactive endogenous radicals. In
the future, this finding must be accompanied by larger studies to fill a
knowledge gap in the scientific literature concerning a holistic
approach of the in vitro antioxidant action of plant polyphenolic
compounds. Conclusively, we believe that wines possess high bioactivity
that allow them to settle in the industry of food additives and
medicinal products."
}