@article{3032369,
    title = "COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and
Weaning",
    author = "Kondili, Eumorfia and Makris, Demosthenes and Georgopoulos, Dimitrios and and Rovina, Nikoletta and Kotanidou, Anastasia and Koutsoukou, Antonia",
    journal = "International Journal of Person-Centered Medicine",
    year = "2021",
    volume = "11",
    number = "11",
    publisher = "MDPI",
    issn = "2043-7730, 2043-7749",
    doi = "10.3390/jpm11111109",
    keywords = "COVID-19; lung injury; mechanical ventilation; weaning",
    abstract = "The COVID-19 disease can cause hypoxemic respiratory failure due to
ARDS, requiring invasive mechanical ventilation. Although early studies
reported that COVID-19-associated ARDS has distinctive features from
ARDS of other causes, recent observational studies have demonstrated
that ARDS related to COVID-19 shares common clinical characteristics and
respiratory system mechanics with ARDS of other origins. Therefore,
mechanical ventilation in these patients should be based on strategies
aiming to mitigate ventilator-induced lung injury. Assisted mechanical
ventilation should be applied early in the course of mechanical
ventilation by considering evaluation and minimizing factors associated
with patient-inflicted lung injury. Extracorporeal membrane oxygenation
should be considered in selected patients with refractory hypoxia not
responding to conventional ventilation strategies. This review
highlights the current and evolving practice in managing mechanically
ventilated patients with ARDS related to COVID-19."
}