@article{3032827, title = "Botulinum toxin type A treatment is associated with improved social and psychological behavior: A retrospective study", author = "Sykianakis, Dimitris and Stratigos, Alexander and Chatziioannou, Argiro and and Christodoulou, Christos", journal = "Journal of Cosmetic Dermatology", year = "2022", volume = "21", number = "1", pages = "142-148", publisher = "Wiley", issn = "1473-2130, 1473-2165", doi = "10.1111/jocd.14627", keywords = "botulinum toxin type A; emotions; face; facial muscles; Onabotulinum toxin; socialization", abstract = "Background The human face significantly affects the individuals’ quality of life, attitude, and mental state. The study of anatomy would always be on the spotlight, as the beauty of the face is desired by humans worldwide. However, age, stress, and negative emotions could lead to stimulation of the corrugator supercilii and procerus muscles in the glabellar region and, subsequently, to alterations in face’s characteristics, which could be associated with isolation and avoidance of engaging in social contacts. Aims Here, we aimed to examine the degree to which treatment with botulinum toxin type A (BoNT A) can affect patients’ quality of life and mental state. Patients/Methods The data collection was performed using 11 questionnaires, which were filled by 83 individuals who underwent BoNT A treatment (sex, 95% female and 5% male; mean age, 48 years). Results The results showed that the treatment with BoNT A improved the patients’ social and psychological behavior, and their opinion regarding their appearance. This effect developed within 1 month following completion of the treatment. Moreover, the effect was higher in patients’ social behavior and was better in patients aged 40-49 years compared to those aged Thus, BoNT A treatment could be considered as an important way to improve the social behavior and socialization of individuals by raising their psychology and self-esteem." }