@article{3032980,
    title = "Precision Medicine in Aortic Anastomosis: A Numerical and Experimental
Study of a Novel Double-Sided Needle",
    author = "Manolesou, Danae G. and Korompili, Georgia and Davazoglou, Dimitris and and Lazaris, Andreas M. and Schizas, Dimitrios and Sanoudou, Despina and and Liakakos, Theodore and Tsioufis, Constantinos and Papaioannou, Theodore and G.",
    journal = "International Journal of Person-Centered Medicine",
    year = "2021",
    volume = "11",
    number = "12",
    publisher = "MDPI",
    issn = "2043-7730, 2043-7749",
    doi = "10.3390/jpm11121385",
    keywords = "vascular surgery; aorta; experimental devices; surgical needle",
    abstract = "Background: Hand-sewn anastomosis is a crucial part of aortic
reconstruction surgery and significantly affects its outcome. The
present study presents a novel, bidirectional surgical needle aimed to
improve aortic anastomosis in terms of speed and ease of use. Our
objective was to assess the efficacy of the new design in comparison
with the conventional needle. Methods: A series of simulations were
conducted with COMSOL software in order to perform a fatigue comparative
analysis between the new and the conventional needle design. Ease of
penetration into a piece of polydimethylsiloxane was evaluated. Lastly,
the prototype was tested under in-vitro conditions in comparison with
the conventional needle. Results: Based on fatigue analysis, the new
needle design improves durability, provided the two tips are equally
used. The polytetrafluoroethylene coating improves penetration into the
tissue by 7% to 17%, while electropolishing improves penetration up to
19%. When using the novel needle design, the average anastomotic task
completion time was significantly reduced by 22% and the overall
distance of hand movements was significantly reduced by 20%.
Conclusions: The proposed design exhibited a shorter anastomotic time
and seems promising in relation to ease of use and simplicity of the
anastomotic technique it introduces."
}