@article{3046160, title = "POLYMORPHONUCLEAR LEUKOCYTE FUNCTIONS AND MULTIPLE-SCLEROSIS", author = "PODIKOGLOU, DG and LIANOU, PE and TSAKANIKAS, CD and PAPAVASSILIOU, JT", journal = "Functional Neurology", year = "1994", volume = "44", number = "1", pages = "129-132", publisher = "LITTLE BROWN CO", doi = "10.1212/WNL.44.1.129", abstract = "We tested peripheral blood from 60 patients with definite multiple sclerosis (MS) and 60 healthy controls for polymorphonuclear leukocyte (PMNL) functions and found significant disorders in adherence (9.07% +/- 8.18% far patients versus 28.97% +/- 5.76% for controls), chemotaxis (18.32 +/- 3.1 for patients versus 30.49 +/- 4.52 for controls), phagocytosis (73.6 +/- 25.25 for patients versus 111.2 +/- 25.7 for controls), and bactericidal action (10.35% +/- 5% for patients versus 25.09% +/- 4.82% for controls). All differences were significant (p < 0.001). We confirmed the results by retesting 3 to 8 months later. The depressed PMNL functions in MS patients may explain their increased susceptibility to infections of the respiratory, digestive, and urinary tracts." }