@article{3046825,
    title = "BIOGENIC-AMINE METABOLITES IN DELUSIONAL (PSYCHOTIC) DEPRESSION AND
MELANCHOLIA SUBTYPES OF MAJOR DEPRESSION",
    author = "LYKOURAS, L and MARKIANOS, M and HATZIMANOLIS, J and MALLIARAS, D and and STEFANIS, C",
    journal = "Progress in Neuro-Psychopharmacology and Biological Psychiatry",
    year = "1994",
    volume = "18",
    number = "8",
    pages = "1261-1271",
    publisher = "PERGAMON-ELSEVIER SCIENCE LTD",
    issn = "0278-5846",
    doi = "10.1016/0278-5846(94)90092-2",
    keywords = "DELUSIONAL DEPRESSION; URINARY HOMOVANILLIC ACID; URINARY
5-HYDROXY-INDOLEACETIC ACID; URINARY 3-METHOXY-4-HYDROXYPHENYLGLYCOL",
    abstract = "1. The levels of the urinary main metabolites of norepinephrine
3-methoxy-n-hydroxyphenylglycol (MHPG), of dopamine homovanillic acid
(HVA) and of serotonin 5-hydroxyindoleacetic acid (5-HIAA) were measured
in 84 patients with major depressive disorder, 34 delusional and 50
nondelusional. Melancholia subtype was also defined (N=62).
2. MHPG was significantly higher in the delusional depressed group
(p=0.023), Female patients with delusional major depression also had
significantly higher HVA excretion than female patients with non
delusional major depression (p=0.036). 5-HIAA excretion was similar in
the two patient subgroups.
3. No significant differences in the three monoamine metabolites were
found between the melancholic and nonmelancholic depressed patients."
}