@article{3048436,
    title = "Regional myocardial motion and thickening assessed at rest by ECG-gated
Tc-99m-MIBI emission tomography and by magnetic resonance imaging",
    author = "Anagnostopoulos, C and Gunning, MG and Pennell, DJ and Laney, R and and Proukakis, H and Underwood, SR",
    journal = "European Journal of Nuclear Medicine and Molecular Imaging",
    year = "1996",
    volume = "23",
    number = "8",
    pages = "909-916",
    publisher = "Springer-Verlag",
    issn = "1619-7070, 1619-7089",
    doi = "10.1007/BF01084364",
    keywords = "myocardial perfusion imaging; gated single-photon emission tomography;
technetium-99m methoxyisobutylisonitrile; magnetic resonance imaging;
left ventricular function",
    abstract = "We have validated EGG-gated emission tomography using technetium-99m
methoxyisobutylisonitrile for the assessment of regional ventricular
function by comparing it with cine magnetic resonance imaging (MRI),
Gated tomography was performed at rest in 24 patients referred for
myocardial perfusion imaging [17 males and seven females with a mean
age of 58 years, nine of whom had had a previous myocardial infarction
(MI)]. Scores were assigned to each of nine myocardial segments for wall
motion and for thickening. Cine MRI was analysed in an identical
fashion. Four out of 216 (2%) segments were uninterpretable by gated
tomography because of inadequate tracer uptake. In eight patients
without coronary artery disease (CAD), wall motion and thickening were
normal by both methods. Gated tomography showed abnormal wall motion or
thickening in all patients with previous MI and in five of seven
patients with CAD but no prior MI. Association between wall motion and
thickening was good (r(s)=0.86). Overall, there was good agreement
between gated tomography and MRI for both wall motion (178/212
kappa=0.66) and wall thickening (184/212 kappa=0.69). In segments with
severely reduced perfusion, however, there was poorer agreement
(kappa=0.31). Interobserver and intraobserver agreement was high (kappa
from 0.61 to 0.78), Thus, in patients investigated for CAD, there is
good overall agreement between gated tomography and MRI but the
agreement is lower in segments with severe perfusion defects."
}