@article{3048522,
    title = "Prophylactic oophorectomy in ovarian cancer prevention",
    author = "Kontoravdis, A and Kalogirou, D and Antoniou, G and Kontoravdis, N and and Karakitsos, P and Zourlas, PA",
    journal = "International Journal of Gynecology and Obstetrics",
    year = "1996",
    volume = "54",
    number = "3",
    pages = "257-262",
    publisher = "ELSEVIER SCI IRELAND LTD",
    issn = "0020-7292",
    doi = "10.1016/0020-7292(96)02724-5",
    keywords = "prophylaxis; ovarian cancer; hysterectomy; oophorectomy",
    abstract = "Objective: To evaluate prophylactic oophorectomy in the prevention of
ovarian cancer. Method: Between 1970 and 1990, 5262 hysterectomies were
performed at Areteion Hospital, Athens. Results. Ovarian cancer was
subsequently diagnosed in 520 women (9.9%), The mean interval from
hysterectomy to diagnosis of ovarian cancer was 7.2 years. If
prophylactic bilateral oophorectomy had been practiced routinely in
women undergoing hysterectomy at age 40 or above, 9.4% of cases would
have been prevented, Conclusion: We recommend bilateral oophorectomy for
all women with a positive family history of ovarian carcinoma and for
all women undergoing hysterectomy after the age of 40. The decision for
prophylactic oophorectomy as a complementary procedure to other
indicated gynecologic surgeries should depend on the individual patient
and her ability to comply with lifelong estrogen replacement therapy."
}