@article{3049201,
    title = "Transvaginal color Doppler and CA125 as tools in the differential
diagnosis of postmenopausal ovarian masses",
    author = "Botsis, D and Kassanos, D and Kalogirou, D and Karakitsos, P and Liapis, and A and Antoniou, G",
    journal = "Maturitas",
    year = "1997",
    volume = "26",
    number = "3",
    pages = "203-209",
    publisher = "ELSEVIER SCI IRELAND LTD",
    issn = "0378-5122",
    doi = "10.1016/S0378-5122(96)01097-3",
    keywords = "transvaginal ultrasonography; ovarian cancer; CA125; color Doppler
imaging",
    abstract = "Objective: To evaluate whether transvaginal color Doppler and CA125 are
valid in differentiating malignant from benign postmenopausal ovarian
masses. Methods: Sixty-two women with ovarian masses were studied with
transvaginal color Doppler ultrasound before surgery, Serum CA125 levels
were also measured, Resistance index (RI) and pulsatility index (PI)
were calculated from the waveforms generated from blood flow within the
ovary. Results: Benign tumors had a significantly higher pulsatility
index (mean 1.23 +/- 1.02; range 0.65-2.99) and resistive index (mean
0.78 +/- 0.22; range 0.5-1.1) than did malignant tumors. However some
overlap in individual values for benign and malignant lesions was found.
RI and PI sensitivity were significantly higher than those with CA125 (P
< 0.05). Blood flow was delectable by color Doppler imaging in 95% of
cases with malignant masses. Conclusion: Doppler sonographic evaluation
of resistance and pulsatility indexes in the vessels of ovarian masses
together with CA125 increased the sensitivity of prediction of
malignancy for pelvic masses, but further work is needed before the
validity of these factors is proved. (C) 1997 Elsevier Science Ireland
Ltd."
}