@article{3051198, title = "Fixed subaortic stenosis revisited - Congenital abnormalities in 72 new cases and review of the literature", author = "Tentolouris, K and Kontozoglou, T and Trikas, A and Brilli, S and and Chlapoutakis, E and Exadactylos, N and Pitsavos, C and Toutouzas, P", journal = "European Cardiology Review", year = "1999", volume = "92", number = "1", pages = "4-10", publisher = "Karger", doi = "10.1159/000006939", keywords = "congenital heart disease; congenital abnormalities; aortic stenosis", abstract = "Seventy-two patients aged 2-65 years (mean 20.2) with fixed subaortic stenosis (FSS) are reported. All patients underwent echocardiography and angiography prior to surgical intervention, Sixty-four (89%) had discrete subaortic stenosis (DSS) and 8 (11%) tunnel type stenosis (TSS). Patients with DSS aged 2-65 years (mean 29) while patients with TSS aged 10-34 years (mean 19) and had a distinct female preponderance (7:1). Twenty-five patients (39%) with DSS had other congenital abnormalities of which aortic stenosis associated with bicuspid aortic valve was slightly more common than ventricular septal defect (7:6), Five patients with TSS had a small aortic annulus and hypoplastic aorta. Our data and those in the literature indicate that TSS although related to DSS has certain features that may set it apart as a distinct entity. In addition DSS appears to be associated with aortic stenosis and bicuspid aortic valve as frequently as with ventricular septal defect. Copyright (C) 2000 S. Karger AG, Basel." }