@article{3051292,
    title = "Exercise-induced ST-segment changes in lead V-1 identify the
significantly narrowed coronary artery in patients with single-vessel
disease - Correlation with thallium-201 scintigraphy and coronary
arteriography data",
    author = "Michaelides, AP and Psomadaki, ZD and Richter, DJ and Dilaveris, PE and and Andrikopoulos, GK and Kakaidis, S and Stefanadis, C and Gialafos, JE and and Toutouzas, PK",
    journal = "Journal of Electrocardiology",
    year = "1999",
    volume = "32",
    number = "1",
    pages = "7-14",
    publisher = "CHURCHILL LIVINGSTONE INC MEDICAL PUBLISHERS",
    issn = "0022-0736, 1532-8430",
    doi = "10.1016/S0022-0736(99)90016-X",
    keywords = "exercise testing; ST-segment changes; lead V-1; coronary; artery disease",
    abstract = "We investigated the correlation of exercise-induced ST-segment changes
in lead V-1, with the detection of the significantly narrowed vessel
that induced ischemia during exercise in myocardial areas supplied by
this vessel. We studied 198 patients who underwent exercise testing,
thallium-201 scintigraphy, and coronary arteriography. The patients were
divided into three groups. In group 1 (ST-segment elevation in lead
V-1), 84% had left anterior descending coronary artery disease (P <
.001); in group 2 (ST-segment depression in lead V-1), 76% had right
coronary artery disease (P < .001); and in group 3 (no ST-segment
changes in lead V-1), there were no significant differences concerning
the narrowed vessel. Thallium-201 scintigraphy data confirmed the
existence of the reversible perfusion defect(s) in an area(s) of
myocardium supplied by the respective coronary arteries (P < .001).
Exercise-induced ST-segment elevation or depresssion in V-1 may identify
the obstructed vessel in patients with single-vessel disease and without
prior myocardial infarction."
}