@article{3063342, title = "Paleo-polyploidization in Lycophytes", author = "Wang, J. and Yu, J. and Sun, P. and Li, C. and Song, X. and Lei, T. and Li, Y. and Yuan, J. and Sun, S. and Ding, H. and Duan, X. and Shen, S. and Shen, Y. and Li, J. and Meng, F. and Xie, Y. and Wang, J. and Hou, Y. and Zhang, J. and Zhang, X. and Li, X.-Q. and Paterson, A.H. and Wang, X.", journal = "Genomics Proteomics and Bioinformatics", year = "2020", volume = "18", number = "3", pages = "333-340", publisher = "Beijing Genomics Institute", issn = "1672-0229", doi = "10.1016/j.gpb.2020.10.002", keywords = "angiosperm; article; human; nonhuman; polyploidy; genetics; genomics; molecular evolution; phylogeny; plant genome; Selaginellaceae, Evolution, Molecular; Genome, Plant; Genomics; Phylogeny; Polyploidy; Selaginellaceae", abstract = "Lycophytes and seed plants constitute the typical vascular plants. Lycophytes have been thought to have no paleo-polyploidization although the event is known to be critical for the fast expansion of seed plants. Here, genomic analyses including the homologous gene dot plot analysis detected multiple paleo-polyploidization events, with one occurring approximately 13–15 million years ago (MYA) and another about 125–142 MYA, during the evolution of the genome of Selaginella moellendorffii, a model lycophyte. In addition, comparative analysis of reconstructed ancestral genomes of lycophytes and angiosperms suggested that lycophytes were affected by more paleo-polyploidization events than seed plants. Results from the present genomic analyses indicate that paleo-polyploidization has contributed to the successful establishment of both lineages—lycophytes and seed plants—of vascular plants. © 2020" }