@article{3078249,
    title = "A Comprehensive Multidisciplinary Management Plan Is Effective in Reducing the Prevalence of Overweight and Obesity in Childhood and Adolescence",
    author = "Genitsaridi, S.-M. and Giannios, C. and Karampatsou, S. and Papageorgiou, I. and Papadopoulos, G. and Farakla, I. and Koui, E. and Georgiou, A. and Romas, S. and Terzioglou, E. and Papathanasiou, C. and Kassari, P. and Manios, Y. and Charmandari, E.",
    journal = "Hormone Research in Paediatrics",
    year = "2020",
    volume = "93",
    number = "2",
    pages = "94-107",
    publisher = "S Karger AG",
    issn = "1663-2818",
    doi = "10.1159/000507760",
    keywords = "25 hydroxyvitamin D;  alanine aminotransferase;  albumin;  alkaline phosphatase;  androstenedione;  apolipoprotein A1;  apolipoprotein B;  aspartate aminotransferase;  C reactive protein;  cholesterol;  corticotropin;  ferritin;  follitropin;  glucose;  glutathione peroxidase;  hemoglobin A1c;  high density lipoprotein cholesterol;  hydrocortisone;  insulin;  lipoprotein;  low density lipoprotein cholesterol;  luteinizing hormone;  prasterone;  prolactin;  testosterone;  thyroglobulin antibody;  thyroid peroxidase antibody;  thyrotropin;  thyroxine;  triacylglycerol, adolescent;  adult;  Article;  body mass;  chemiluminescence immunoassay;  child;  childhood obesity;  female;  follow up;  hip circumference;  HOMA index;  human;  hydrocortisone blood level;  major clinical study;  male;  multidisciplinary team;  obesity;  physical activity;  prevalence;  priority journal;  prospective study;  psychologic assessment;  waist circumference;  young adult;  childhood obesity;  disease management;  Greece;  obesity;  preschool child;  prevalence, Adolescent;  Body Mass Index;  Child;  Child, Preschool;  Disease Management;  Female;  Greece;  Humans;  Male;  Overweight;  Pediatric Obesity;  Prevalence",
    abstract = "Background: Obesity in childhood and adolescence represents a major health problem of our century. In Greece, 30-35% of children and adolescents are overweight or obese. Objective and Hypotheses: To investigate the effectiveness of a comprehensive multidisciplinary personalized management plan at reducing the prevalence of overweight and obesity in childhood and adolescence. Patients and Methods: One thousand (n = 1,000) children and adolescents aged 2-18 years (mean age ± SD: 10.09 ± 2.86 years; 520 females, 480 males) were studied prospectively. Subjects were classified as obese (n = 579, 57.9%), overweight (n = 295, 29.5%) or having a normal body mass index (BMI) (n = 126, 12.6%) according to the International Obesity Task Force cutoff points. All subjects were evaluated by a multidisciplinary team at frequent intervals, received personalized advice on diet and exercise and were studied prospectively for 1 year. Detailed clinical evaluation and laboratory investigations were performed at the beginning and at the end of the study. Results: At initial evaluation, 57.9% of subjects were obese, 29.5% overweight and 12.6% of normal BMI. Indices of cardiometabolic disease were higher in obese than in overweight and normal-BMI subjects. Following 1 year of multidisciplinary management interventions, the prevalence of obesity decreased by 16.8%, the prevalence of normal BMI increased by 8.2%, and all cardiometabolic indices improved significantly. Conclusions: A personalized multidisciplinary management plan is effective at reducing the prevalence of obesity in childhood and adolescence. © 2020 S. Karger AG. All rights reserved."
}