@article{3078824,
    title = "Chronic administration of plasma from exercised rats to sedentary rats does not induce redox and metabolic adaptations",
    author = "Goutianos, G. and Margaritelis, N.V. and Sparopoulou, T. and Veskoukis, A.S. and Vrabas, I.S. and Paschalis, V. and Nikolaidis, M.G. and Kyparos, A.",
    journal = "The Journal of Physiological Sciences",
    year = "2020",
    volume = "70",
    number = "1",
    publisher = "BioMed Central Ltd.",
    issn = "1880-6546, 1880-6562",
    doi = "10.1186/s12576-020-00737-2",
    keywords = "antioxidant, adaptation;  animal;  animal experiment;  male;  metabolism;  oxidation reduction reaction;  plasma;  rat;  swimming;  Wistar rat, Adaptation, Physiological;  Animals;  Antioxidants;  Male;  Oxidation-Reduction;  Physical Conditioning, Animal;  Plasma;  Rats;  Rats, Wistar;  Swimming",
    abstract = "The present study aimed to investigate whether endurance exercise-induced changes in blood plasma composition may lead to adaptations in erythrocytes, skeletal muscle and liver. Forty sedentary rats were randomly distributed into two groups: a group that was injected with pooled plasma from rats that swam until exhaustion and a group that was injected with the pooled plasma from resting rats (intravenous administration at a dose of 2 mL/kg body weight for 21 days). Total antioxidant capacity, malondialdehyde and protein carbonyls were higher in the plasma collected from the exercised rats compared to the plasma from the resting rats. Νo significant difference was found in blood and tissue redox biomarkers and in tissue metabolic markers between rats that received the "exercised" or the "non-exercised" plasma (P > 0.05). Our results demonstrate that plasma injections from exercised rats to sedentary rats do not induce redox or metabolic adaptations in erythrocytes, skeletal muscle and liver. © 2020 The Author(s)."
}