@article{3081291, title = "Epidermolysis bullosa acquisita: treatment with intravenous immunoglobulins", author = "Gourgiotou, K and Exadaktylou, D and Aroni, K and Rallis, E and and Nicolaidou, E and Paraskevakou, H and Katsambas, AD", journal = "Journal of the European Academy of Dermatology and Venereology", year = "2002", volume = "16", number = "1", pages = "77-80", publisher = "EUROPEAN ACAD DERMATOLOGY & VENEREOLOGY", issn = "0926-9959, 1468-3083", doi = "10.1046/j.1468-3083.2002.00386.x", keywords = "epidermolysis bullosa acquisita; intravenous immunoglobutins", abstract = "Epidermolysis bullosa acquisita (EBA) is a rare autoimmune bullous disorder that is often difficult to treat. Few cases have been reported and therapy consists mainly of combinations of systemic steroids, immunosuppressants and, recently, administration of intravenous human immunoglobulin (IVIg). We describe a case of EBA in which our therapeutic choices were limited due to the patient’s poor general condition, including extensive infection of the lesions and a history of pulmonary tuberculosis. The patient was treated with IVIg at a dose of 400 mg/kg per day for 5 consecutive days every 4 weeks. The treatment was wen tolerated and the results were satisfactory. It seems that IVIg, due to its possible immunomodulatory mode of action, can be an efficacious therapeutic agent in this rare autoimmune disease." }