@article{3082842,
    title = "Primitive neuroectodermal tumour in a 60-year-old man: a case report and
literature review",
    author = "Balafouta, MJ and Kouvaris, JR and Miliadou, AC and Papacharalampous, XN and and Kolokouris, DV and Kouloulias, VE and Mariolis, AD and Vlahos, LJ",
    journal = "The British Journal of Radiology",
    year = "2003",
    volume = "76",
    number = "901",
    pages = "62-65",
    publisher = "BRITISH INST RADIOLOGY",
    issn = "0007-1285, 1748-880X",
    doi = "10.1259/bjr/47707206",
    abstract = "Primitive neuroectodermal tumour (PNET) is very rare, especially in
adults. We report a 60-year-old man presented with a PNET. The symptoms
at the time of diagnosis were intense headache, Broca’s aphasia and
right hemiparesis. Only an open biopsy was performed. Irradiation of the
primary tumour was the main treatment (total tumour dose 59.8 Gy)
because of serious haematological side effects due to chemotherapy. The
patient tolerated radiation therapy extremely well and his neurological
symptoms were improved. I month after completion of radiotherapy, MRI
showed no regression of the tumour. Clinical deterioration was observed
10 months after the initial diagnosis and the patient died 2 months
later. In cases of PNET, initial therapy is surgical bulk reduction
whenever possible. Irradiation of the cerebrospinal axis is justified as
a routine treatment but, owing to the radioresistance of the turnout,
the addition of multiregimen chemotherapy appears to improve survival,
according to the literature."
}