@article{3083487, title = "Mesenteric lymphadenopathy as a cause of abdominal pain in children with lobar or segmental pneumonia", author = "Moustaki, M and Zeis, PM and Katsikari, M and Fretzayas, A and Grafakou, and O and Stabouli, S and Tsolia, M and Nicolaidou, P and Karpathios, T", journal = "Pediatric Pulmonology", year = "2003", volume = "35", number = "4", pages = "269-273", publisher = "Wiley-Liss, Inc.", issn = "8755-6863, 1099-0496", doi = "10.1002/ppul.10254", keywords = "mesenteric lymphadenopathy; abdominal pain; pneumonia; ultrasound", abstract = "We investigated whether mesenteric lymphadenopathy could be a cause of abdominal pain in children with lobar or segmental pneumonia. The study population consisted of 1)119 consecutive children with lobar pneumonia, older than 4 years of age, and 2) 31 healthy controls. Demographic, clinical, inflammatory, and radiographic data were recorded in all patients. All study subjects underwent abdominal ultrasound, focusing on the identification of mesenteric lymphadenopathy. One month later, a follow-up ultrasound was performed in patients with enlarged mesenteric lymph nodes at the initial examination. Forty patients complaining of abdominal pain were included in group I, while the remaining 79 were in group 2. The two groups of patients did not significantly differ regarding their demographic, clinical (other than abdominal pain), and radiographic indices. In contrast, enlarged mesenteric lymph nodes with a sagittal diameter of at least 10 mm were identified significantly more commonly in the children of group I (P = 0.001). The association of enlarged lymph nodes with the presence of abdominal pain remained significant when the data were analyzed through multiple regression analysis (odds raio, 1.47; 95% confidence interval, 3-44). Enlarged mesenteric lymph nodes were found in a significantly lower ratio of healthy controls (3/31) compared to that observed in group I (P = 0.003). In all patients who were followed up, mesenteric lymph nodes had either decreased or were not detectable. Our findings indicate that mesenteric lymphadenopathy might be considered as a mechanism responsible for the development of abdominal pain in a relatively high percentage of children with pneumonia. Pediatr Pulmonol. 2003; 35:269-273. (C) 2003Wiley-Liss, Inc." }