@article{3085508,
    title = "Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection",
    author = "Bøtker, H.E. and Hausenloy, D. and Andreadou, I. and Antonucci, S. and Boengler, K. and Davidson, S.M. and Deshwal, S. and Devaux, Y. and Di Lisa, F. and Di Sante, M. and Efentakis, P. and Femminò, S. and García-Dorado, D. and Giricz, Z. and Ibanez, B. and Iliodromitis, E. and Kaludercic, N. and Kleinbongard, P. and Neuhäuser, M. and Ovize, M. and Pagliaro, P. and Rahbek-Schmidt, M. and Ruiz-Meana, M. and Schlüter, K.-D. and Schulz, R. and Skyschally, A. and Wilder, C. and Yellon, D.M. and Ferdinandy, P. and Heusch, G.",
    journal = "Basic Research in Cardiology",
    year = "2018",
    volume = "113",
    number = "5",
    publisher = "Dr. Dietrich Steinkopff Verlag GmbH and Co. KG",
    issn = "0300-8428, 1435-1803",
    doi = "10.1007/s00395-018-0696-8",
    keywords = "1,2,3,6 tetrahydro 1 methyl 4 phenylpyridine;  biological marker;  calcein;  calcium;  reactive oxygen metabolite;  reagent;  cardiovascular agent, analytical parameters;  animal cell culture;  calcium homeostasis;  cardiac muscle cell;  cardiovascular magnetic resonance;  cell death;  cell isolation;  cell membrane permeability;  cell viability;  cells by body anatomy;  cellular parameters;  clinical protocol;  coronary artery blood flow;  data analysis;  disease duration;  effect size;  electrocardiography;  endothelium cell;  endotracheal intubation;  epitranscriptomics;  exosome;  experimental study;  exploratory research;  H9c2(2-1) cell line;  heart contraction;  heart infarction;  heart infarction size;  heart left ventricle;  heart mitochondrion;  heart muscle blood flow;  heart muscle fiber membrane;  heart muscle oxygen consumption;  heart pacing;  heart protection;  heart surgery;  heart tissue;  heart ventricle;  HL-1 cell line;  human;  isolated heart;  mathematical computing;  metabolomics;  methodology;  mitochondrial membrane potential;  mitochondrial permeability;  mitochondrion swelling;  myocardial ischemia reperfusion injury;  nonhuman;  nonparametric test;  parametric test;  pathological anatomy;  pathophysiology;  practice guideline;  prospective study;  randomization;  reoxygenation;  reproducibility;  Review;  RNA isolation;  sample size;  statistical analysis;  statistical parameters;  statistics;  stem cell;  temperature measurement;  thermoregulation;  transcriptomics;  animal;  cardiology;  disease model;  heart infarction;  heart infarction prevention;  measurement accuracy;  medical research;  metabolism;  myocardial ischemia reperfusion injury;  pathology;  practice guideline;  preclinical study;  procedures;  reproducibility;  standards, Animals;  Biomedical Research;  Cardiology;  Cardiovascular Agents;  Data Accuracy;  Data Interpretation, Statistical;  Disease Models, Animal;  Drug Evaluation, Preclinical;  Humans;  Ischemic Preconditioning, Myocardial;  Myocardial Infarction;  Myocardial Reperfusion Injury;  Reproducibility of Results;  Research Design"
}