@article{3085597,
    title = "Athlome project consortium: A concerted effort to discover genomic and other "omic" markers of athletic performance",
    author = "Pitsiladis, Y.P. and Tanaka, M. and Eynon, N. and Bouchard, C. and North, K.N. and Williams, A.G. and Collins, M. and Moran, C.N. and Britton, S.L. and Fuku, N. and Ashley, E.A. and Klissouras, V. and Lucia, A. and Ahmetov, I.I. and De Geus, E. and Alsayrafi, M. and Webborn, N. and Wang, G. and Bishop, D.J. and Papadimitriou, I. and Yan, X. and Tirosh, O. and Kuang, J. and Rankinen, T. and Sarzinsky, M. and Mikael Mattsson, C. and Wheeler, M. and Waggott, D. and Byrne, N.M. and Artioli, G.G. and September, A. and Posthumus, M. and Van der Merwe, W. and Cieszczyk, P. and Leonska-Duniec, A. and Ficek, K. and Maciejewska-Karlowska, A. and Sawczuk, M. and Stepien-Slodkowska, M. and Feller, J. and Dijkstra, P. and Chmutov, A.M. and Dyatlov, D.A. and Orekhov, E.F. and Pushkareva, Y.E. and Shvedkaya, I.A. and Massidda, M. and Calò, C.M. and Day, S.H. and Stebbings, G.K. and Erskine, R.M. and Montgomery, H.E. and Garton, F.C. and Houweling, P. and Derave, W. and Baguet, A. and Muniesa, C.A. and Sessa, F. and Petito, A. and Sale, C. and Hughes, D.C. and Varley, I. and Boomsma, D. and Bartels, M. and Davies, G.E. and Ginevičienė, V. and Jakaitienė, A. and Kučinskas, V. and Tubelis, L. and Utkus, A. and Milašius, K. and Venckunas, T. and Skurvydas, A. and Stasiulis, A. and Malkova, D. and Wilson, R. and Koch, L.G. and Zempo, H. and Naito, H. and Kikuchi, N. and Miyamoto-Mikami, E. and Murakami, H. and Miyachi, M. and Takahashi, H. and Ohiwa, N. and Kawahara, T. and Tsuchie, H. and Tobina, T. and Ichinoseki-Sekine, N. and Tanaka, H. and Kaneoka, K. and Nakazato, K. and Egorova, E.S. and Gabdrakhmanova, L.J. and Arkhipova, A.A. and Borisova, A.V. and Gabbasov, R.T. and Stepanova, A.A. and Kashapov, R.I. and Rogozkin, V.A. and Astratenkova, I.V. and Druzhevskaya, A.M. and Fedotovskaya, O.N. and Golberg, N.D. and Hakimullina, A.M. and Kostryukova, E.S. and Alexeev, D.G. and Generozov, E.V. and Ischenko, D.S. and Kulemin, N.A. and Larin, A.K. and Ospanova, E.A. and Pavlenko, A.V. and Govorun, V.M. and Gilep, A.A. and Gilep, I.L. and Haidukevich, I.V. and Rybina, I.L. and Drozdovska, S.B. and Docenko, V.E. and Ilyin, V.N. and Lekontsev, E. and Akimov, E.B. and El-Rayess, M. and Georgakopoulos, C. and Botre, F. and Suhre, K. and Hubank, M. and Wolfarth, B. and Greeves, J.P. and Stellingwerff, T. and Ranson, C. and Fraser, W.D. and Grealy, R. and Griffiths, L. and Scott, R. and Pushkarev, V.P. and Athlome Project Consortium",
    journal = "Physiological Genomics",
    year = "2016",
    volume = "48",
    number = "3",
    pages = "183-190",
    publisher = "American Physiological Society",
    issn = "1094-8341, 1531-2267",
    doi = "10.1152/physiolgenomics.00105.2015",
    keywords = "athletic performance;  basic research;  DNA modification;  ethnic difference;  exercise;  gene frequency;  gene linkage disequilibrium;  genetic association;  genetic association study;  genetic marker;  genetic predisposition;  genetic variability;  human;  indel mutation;  priority journal;  Review;  single nucleotide polymorphism;  animal;  Europe;  genetic epigenesis;  genomics;  metabolism;  procedures;  tissue bank, biological marker, Animals;  Athletic Performance;  Biomarkers;  Epigenesis, Genetic;  Europe;  Genomics;  Humans;  Tissue Banks",
    abstract = "Despite numerous attempts to discover genetic variants associated with elite athletic performance, injury predisposition, and elite/world-class athletic status, there has been limited progress to date. Past reliance on candidate gene studies predominantly focusing on genotyping a limited number of single nucleotide polymorphisms or the insertion/deletion variants in small, often heterogeneous cohorts (i.e., made up of athletes of quite different sport specialties) have not generated the kind of results that could offer solid opportunities to bridge the gap between basic research in exercise sciences and deliverables in biomedicine. A retrospective view of genetic association studies with complex disease traits indicates that transition to hypothesis-free genome-wide approaches will be more fruitful. In studies of complex disease, it is well recognized that the magnitude of genetic association is often smaller than initially anticipated, and, as such, large sample sizes are required to identify the gene effects robustly. A symposium was held in Athens and on the Greek island of Santorini from 14 -17 May 2015 to review the main findings in exercise genetics and genomics and to explore promising trends and possibilities. The symposium also offered a forum for the development of a position stand (the Santorini Declaration). Among the participants, many were involved in ongoing collaborative studies (e.g., ELITE, GAMES, Gene SMART, GENESIS, and POWERGENE). A consensus emerged among participants that it would be advantageous to bring together all current studies and those recently launched into one new large collaborative initiative, which was subsequently named the Athlome Project Consortium. © 2016 the American Physiological Society."
}