@article{3086050, title = "Gastric Carcinoids", author = "Grozinsky-Glasberg, S. and Alexandraki, K.I. and Angelousi, A. and Chatzellis, E. and Sougioultzis, S. and Kaltsas, G.", journal = "Endocrinology and Metabolism Clinics of North America", year = "2018", volume = "47", number = "3", pages = "645-660", publisher = "W.B. Saunders", issn = "0889-8529", doi = "10.1016/j.ecl.2018.04.013", keywords = "alpha interferon; peptide; proton pump inhibitor; somatostatin derivative; temozolomide, autoimmune disease; biochemistry; cancer grading; cancer prognosis; cancer staging; clinical feature; computer assisted tomography; disease association; endocrine disease; endoscopic mucosal resection; endoscopic submucosal dissection; endoscopic ultrasonography; follow up; gastrectomy; gastroenteropancreatic neuroendocrine tumor; gastroscopy; genetics; histopathology; human; hypergastrinemia; hypothyroidism; incidence; nonhuman; nuclear magnetic resonance imaging; pathogenesis; positron emission tomography-computed tomography; priority journal; Review; stomach carcinoid; stomach carcinoma; adenocarcinoma; carcinoid; gastrointestinal tumor; neuroendocrine tumor; pathology; stomach tumor; tumor recurrence, Adenocarcinoma; Carcinoid Tumor; Gastrointestinal Neoplasms; Humans; Neoplasm Recurrence, Local; Neuroendocrine Tumors; Stomach Neoplasms", abstract = "Gastric carcinoids, formally named gastric neuroendocrine neoplasms (NENs), are derived from enterochromaffin-like cells of the stomach and are increasingly diagnosed. A majority are designated as type I (related to autoimmune gastritis) and type II (related to gastrinoma) neoplasms that develop secondary to gastrin hypersecretion. Types I and II gastric carcinoids are mostly small-sized (1–2 cm), multiple, low-malignancy potential lesions mainly confined to the gastric mucosa/submucosa. These lesions have an indolent course and low metastatic potential. In contrast, type III gastric carcinoids are single, larger-sized (>2 cm), non–gastrin-related lesions that infiltrate the muscular layers associated with local and distant metastases. © 2018 Elsevier Inc." }