@article{3093527,
    title = "Primary malignant mesothelioma of the peritoneum: a clinical and
immunohistochemical study",
    author = "Markaki, S and Protopapas, A and Milingos, S and Lazaris, D and and Antsaklis, A and Michalas, S",
    journal = "Gynecologic Oncology",
    year = "2005",
    volume = "96",
    number = "3",
    pages = "860-864",
    publisher = "ACADEMIC PRESS INC ELSEVIER SCIENCE",
    issn = "0090-8258, 1095-6859",
    doi = "10.1016/j.ygyno.2004.11.014",
    keywords = "malignant mesothelioma; peritoneum; immunohistochemistry",
    abstract = "Background. Primary peritoneal mesothelioma is regarded as a fatal
disease that presents with progressive ascites at a relatively late
stage of its natural history. Differential diagnosis between this rare
tumor and both serous papillary carcinoma of the peritoneum and ovary
can be problematic.
Case. A 54-year-old woman presented to our institution with a 4-month
history of dull epigastric pain and increased abdominal girth.
Exploratory laparotomy revealed the presence of extensive
intraperitoneal dissemination of a malignant neoplasm without a
recognizable primary site. Suboptimal cytoreduction was carried out, and
histological diagnosis was that of a malignant epithelioid mesothelioma.
This was confirmed with a panel of immunohistochemical markers. The
patient despite having a complete response after adjuvant chemotherapy
died 18 months after primary surgery.
Conclusion. No single immunohistochemical stain is pathognomonic of
peritoneal primary malignant mesothelioma (PMM), and the results of a
panel of antibodies should be interpreted to set the diagnosis. (c) 2004
Published by Elsevier Inc."
}