@article{3093888, title = "Microalbuminuria: A strong predictor of 3-year adverse prognosis in nondiabetic patients with acute myocardial infarction", author = "Koulouris, S and Lekatsas, I and Karabinos, I and Ioannidis, G and and Katostaras, T and Kranidis, A and Triantafillou, K and Thalassinos, N and and Anthopoulos, L", journal = "American Heart Journal", year = "2005", volume = "149", number = "5", pages = "840-845", publisher = "Mosby Year Book Inc", issn = "0002-8703, 1097-6744", doi = "10.1016/j.ahj.2004.07.031", abstract = "Background The aim of this study is to evaluate the significance of microalbuminuria (MA) as a 3-year prognostic index in nondiabetic patients with acute myocardial infarction (AMI). Methods One hundred seventy-five patients with AMI were followed prospectively for 3 years. The study end point was cardiac death or rehospitalization for an acute coronary event. Results Forty-two patients (24%) developed a new cardiac event during the follow-up. Microalbuminuria (P < .001), pulmonary edema during initial hospitalization (P < .001) and postinfarction angina (P = .0364), advanced age (P = .001), severe atherosclerosis (high Gensini score) (P = .036), ejection fraction <50% (P = .0013), history of bypass surgery (P = .0265), and early conservative management (P = .021 A) were all associated with adverse prognosis. Cox proportional hazards regression analysis showed that MA was an independent predictor of 3-year adverse prognosis in all the models tested, with an adjusted relative risk for the development of a cardiac event ranging from 2.1 to 4.3. Conclusions In nondiabetic patients with AMI, MA is a strong and independent predictor of an adverse cardiac event within the next 3 years." }