@article{3093973, title = "Positive Tc-99m-MIBI scan in a patient with confirmed Paget's disease of bone", author = "Zanglis, A and Andreopoulos, D and Zissimopoulos, A and Baziotis, N", journal = "Clinical Nuclear Medicine", year = "2005", volume = "30", number = "5", pages = "363-364", publisher = "Lippincott, Williams & Wilkins", issn = "0363-9762, 1536-0229", doi = "10.1097/01.rlu.0000159911.89757.a6", keywords = "Tc-99m-MIBI; Pagets", abstract = "A 46-year-old man was referred to our department for a Tc-99m MDP bone scan after he was admitted to our hospital with diffuse bone pain and the subsequent finding of multiple mixed type (lytic-blastic) lesions on routine x-rays. The Tc-99m MDP scan was highly suspicious for malignancy and, therefore, a Tc-99m MIBI scan was performed, which also revealed abnormal uptake in all regions with increased osteoblastic activity. Clinical chemistry and further workup revealed a highly elevated serum alkaline phosphatase and increased excretion of hydroxyproline in the urine. The presumed diagnosis of Paget’s disease of the bone was further confirmed by biopsy." }